Examples of 'pasireotide' in a sentence
Meaning of "pasireotide"
Pasireotide is a medication used to treat certain conditions such as Cushing's disease or acromegaly
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- An orphan drug used to treat Cushing's disease.
How to use "pasireotide" in a sentence
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pasireotide
Pasireotide works in a very similar way to somatostatin.
It is unknown whether pasireotide is excreted in human milk.
Anticipated pharmacokinetic interactions resulting in effects on pasireotide.
Pasireotide did not affect insulin sensitivity.
It contains the active substance pasireotide.
Pasireotide may decrease the relative bioavailability of ciclosporin.
Most preferred are octreotide and pasireotide.
Pasireotide was not genotoxic in in vitro and in vivo assays.
The active substance is pasireotide.
Pasireotide binds with high affinity to four of the five hssts.
No studies have been conducted to evaluate the bioavailability of pasireotide in humans.
Pasireotide intramuscular use n.
Signifor is a medicine that contains the active substance pasireotide.
Pasireotide or a pharmaceutically acceptable salt thereof for use in the treatment of meningioma.
Available toxicological data in animals have shown excretion of pasireotide in milk.
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Pharmacokinetic steady state for pasireotide intramuscular use is achieved after three months.
Renal clearance has a minor contribution to the elimination of pasireotide in humans.
The relative bioavailability of pasireotide intramuscular use over pasireotide subcutaneous use is complete.
Episodes of torsade de pointes were not observed in any clinical study with pasireotide.
Pasireotide LAR is a long acting formulation of pasireotide which addresses some of the above issues.
Mild transient elevations in aminotransferases are commonly observed in patients treated with pasireotide.
Population PK analyses of pasireotide intramuscular use suggest that race does not influence PK parameters.
There is a limited amount of data from the use of pasireotide in pregnant women.
Like somatostatin, pasireotide attaches to these receptors.
Infrequent cases of hypocortisolism have been reported in clinical studies with pasireotide in acromegaly patients.
Pasireotide is a novel cyclohexapeptide, injectable somatostatin analogue.
Asymptomatic elevations in lipase and amylase were observed in patients receiving pasireotide in clinical studies.
Pasireotide for intramuscular use is formulated as microspheres for long-acting release.
No clinical studies in subjects with liver impairment have been performed with pasireotide intramuscular use.
Based on in vitro data pasireotide appears to be a substrate of efflux transporter P-gp P-glycoprotein.
The study met its primary efficacy endpoint for both pasireotide intramuscular use doses.
The efficacy of pasireotide intramuscular use has been demonstrated in two phase III, multicentre studies.
No change in the pharmacokinetics ( rate or extent of exposure ) of pasireotide was observed.
One vial contains 20 mg pasireotide as pasireotide pamoate.
Examples of somatostatin analogues include octreotide, lanreotide, pasireotide and the like.
Maximum allowed dose was 60 mg for pasireotide intramuscular use and 30 mg for octreotide intramuscular use.
Preferably the active agent is selected from octreotide, pasireotide and mixtures thereof.
The starting dose was 40 mg for pasireotide intramuscular use and 20 mg for octreotide intramuscular use.
Additionally, tolerability and repeated dose toxicity studies were conducted with pasireotide via the intramuscular route.
Ms in 1 patient in the pasireotide intramuscular use 40 mg group.
What Signifor contains - The active substance is pasireotide.
Use with Pasireotide.
Signifor 20 mg powder for injection pasireotide.
The active substance in Signifor, pasireotide is a somatostatin analogue.
Signifor 20 mg powder and solvent for suspension for injection pasireotide.
Ml solution for injection contains 0.3 mg pasireotide as pasireotide diaspartate.
Patients receive pasireotide subcutaneously at a dose of 1200 µg twice daily.
Table 1 Adverse reactions by preferred term for pasireotide intramuscular use.
In healthy volunteers, pasireotide is widely distributed with large apparent volume of distribution Vz / F > 100 litres.
Bradycardia has been reported with the use of pasireotide see section 4.8.
