Examples of 'pivaloyl' in a sentence
Meaning of "pivaloyl"
Pivaloyl is a chemical compound that is used in organic synthesis and pharmaceutical manufacturing. It is a derivative of pivalic acid and has various industrial applications
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- The radical derived from pivalic acid
How to use "pivaloyl" in a sentence
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pivaloyl
Acetyl and pivaloyl are examples of acyl groups.
The mixed anhydride was formed using pivaloyl chloride.
Addition of pivaloyl chloride to the aniline was exothermic.
More particularly preferred is pivaloyl chloride.
Pivaloyl chloride is an important synthetic intermediate in the chemical industry.
Particularly preferred are pivaloyl chloride and ethyl chloroformate.
Especially preferred is acetyl or pivaloyl.
Replacement of pivaloyl chloride by ethyl chloroformate was also not effective.
Substituted anilines give corresponding pivaloyl protected anilines.
Pivaloyl chloride in THF can be used to catalyze the coupling reaction.
The more preferred acid halide is acetyl or pivaloyl chlorides.
In a yet further embodiment pivaloyl chloride in THF are used to catalyze the coupling reaction.
Fluorescent dyes such as fluorescein can be effectively protected by pivaloyl.
A process for the production of pivaloyl chloride comprising the steps of.
In some embodiments, a suitable acyl chloride is pivaloyl chloride.
See also
Benzoyl, pivaloyl and amidine groups can be removed by treatment with concentrated aqueous ammonia.
Continuous process for the preparation of pivaloyl chloride and of aroyl chloride.
Examples of such groups include acetyl, propionyl and pivaloyl.
In one embodiment, the activator used is pivaloyl chloride or adamantane carboxyl chloride in pyridine-acetonitrile.
Therefore, attention focussed on the pivaloyl group.
The pivaloyl ( abbreviated Piv or Pv ) group is a protective group for alcohols in organic synthesis.
The coupling is accomplished by using a condensing reagent, such as pivaloyl chloride.
Beside DCC / DMAP also pivaloyl chloride / DMAP has been examined as effective coupling agents.
Further, the modifying moiety may include a hydrophobic group, such as a pivaloyl group.
Preferred acylating agents are pivaloyl chloride, 2-ethyl-hexanoyl chloride and benzoyl chloride.
Particular protecting groups that may be mentioned include acetyl, t-butoxycarbonyl and pivaloyl.
However, this process has the disadvantage of resulting in a pivaloyl chloride which can comprise sulphur.
Lower alkanoyl is preferably acetyl, propionyl, butyryl, or pivaloyl.
Step 1 requires the reagents pivaloyl chloride, triethylamine and DCM.
Examples of acyl groups include in particular the formyl, acetyl, propanoyl and pivaloyl groups.
In an alternative embodiment, R is a pivaloyl group or an alkyl-pivaloyl group.
I in the above scheme represents any desired leaving group, for example a pivaloyl group.
Addition of 2.0 g of pivaloyl chloride was exothermic, and produced a dense precipitate.
Examples of condensing agents include acid chlorides and phosphoric chloride, preferably pivaloyl chloride.
Pivaloyl chloride, tosyl chloride, mesyl chloride, etc . or an acid derivative e . g.
As such protective groups, for example, an acetyl group and a pivaloyl group can be illustrated.
Interestingly, the pivaloyl group undergoes O → O-acyl migration during the cyclization step ( c ).
Isolating the pivalic acid ; and ii converting pivalic acid obtained in step i into pivaloyl chloride.
The acid chloride reagent can comprise pivaloyl chloride or 2, 4, 6-trimethylbenzoyl chloride.
Examples of the lower alkanoyl group include formyl, acetyl, propionyl and butyryl and pivaloyl groups.
Preferably, R1 is pivaloyl or t-butoxycarbonyl, more preferably R1 is pivaloyl.
A method in accordance with Claim 1 wherein said acetoacetate is t-butyl pivaloyl acetate.
Examples thereof include, for example, an acetyl group, a pivaloyl group, benzoyl group, and the like.
Typical examples are formyl, acetyl, propionyl, butyryl or pivaloyl.
Particularly preferred as nitrogen protecting groups are pivaloyl and t-butoxycarbonyl ( BOC ).
It includes for example acetyl, propanoyl, butanoyl or pivaloyl.
After the gas evolution had subsided, 0.14 grams of pivaloyl chloride were added.
Lower alkanoyl is especially formyl or, more especially, acetyl, propionyl or pivaloyl.
Acid halide or acid anhydride employed, pivaloyl chloride ;.
R5 is an acyl type protecting group, such as acetyl, benzoyl, trichloroacetyl and pivaloyl.
