Examples of 'plasma kallikrein' in a sentence
Meaning of "plasma kallikrein"
plasma kallikrein - a protease enzyme that plays a role in the kinin-kallikrein system
How to use "plasma kallikrein" in a sentence
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plasma kallikrein
Plasma kallikrein binding proteins may be antibodies.
Lanadelumab inhibits active plasma kallikrein proteolytic activity.
Plasma kallikrein has been implicated in rheumatoid arthritis.
Prekallikrein is the precursor of plasma kallikrein.
Plasma kallikrein is thought to play a role in a number of inflammatory disorders.
Gene structure and chromosomal localization of plasma kallikrein.
Recent information suggests that plasma kallikrein is involved in inflammation.
Several groups have disclosed synthetic inhibitors of plasma kallikrein.
A number of exemplary plasma kallikrein binding proteins are described herein.
Bikunin activity was measured in vitro by its inhibition of human plasma kallikrein.
Inhibition of plasma kallikrein by lanadelumab can increase aPTT in this assay.
Numerous methods are available for immobilizing plasma kallikrein to a solid support.
A plasma kallikrein binding protein can also be modified as a HESylation derivative.
Activation of factor XIIa and human plasma kallikrein were measured as follows.
The plasma kallikrein binding protein can be administered in a therapeutically effective amount.
See also
These residues are distal from the active site of plasma kallikrein.
The active site of plasma kallikrein is contained in the light chain.
The same chromogenic substrate is also recognized and modified by plasma kallikrein.
Plasma kallikrein inhibitors are considered to be especially useful in the treatment of hereditary angioedema.
The compounds of the present invention are potent and selective inhibitors of plasma kallikrein.
The plasma kallikrein binding protein can also be immobilized on a protein array.
The binding proteins can also be evaluated for selectivity toward plasma kallikrein.
Human plasma kallikrein plays a key role in the first events in contact activation.
The experiments were performed essentially as described for plasma kallikrein only appropriate substrates were used.
Plasma kallikrein and tissue kallikrein are distinct enzymes that are activated by different mechanisms.
Also featured is a method for detecting the presence of plasma kallikrein expressing tissues in vivo.
A plasma kallikrein binding protein described herein can also be used to promote wound healing.
The suspension of kaolin was added the mixture to initiate the reaction producing plasma kallikrein.
The plasma kallikrein binding protein can be formulated together with a pharmaceutically acceptable carrier.
Ecallantide suppresses this pathogenetic mechanism by selectively and reversibly inhibiting the activity of plasma kallikrein.
The method can include localizing plasma kallikrein within a subject or within a sample from a subject.
Vi It has an inhibitory action on the production of plasma kallikrein.
Processes for HESylation of a plasma kallikrein binding protein utilize hydroxyethyl starch to modify the protein.
The second agent or therapy can also be another agent for a plasma kallikrein associated therapy.
Plasma kallikrein cleaves HMWK to liberate bradykinin.
Human chymotrypsin and plasma kallikrein were purchased from Sigma.
TAKHZYRO is a type of protein that blocks the activity of plasma kallikrein.
Inhibitors of tissue kallikrein displaying poor plasma kallikrein activity have previously been reported M.
Proteases that have Kallikrein like activity include tissue kallikrein and plasma kallikrein.
In some embodiments, the plasma kallikrein binding protein is an antibody.
Neither LACI nor any of the KuDoms of LACI is a potent plasma kallikrein inhibitor.
In one case, the plasma kallikrein binding protein is a monoclonal antibody.
In one embodiment, the serine protease is plasma kallikrein.
In one embodiment, the plasma kallikrein binding protein is a monoclonal antibody.
In some embodiments, the protein inhibits plasma kallikrein.
To target plasma kallikrein expressing cells, a prodrug system can be used.
In some cases, the protein inhibits plasma kallikrein.
It is preferred that a plasma kallikrein binding protein be substantially pure and / or sterile.
Furthermore, some of the compounds also inhibit plasma kallikrein.
During attacks, unregulated activity of plasma kallikrein results in excessive bradykinin generation.
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Plasma concentrations are similar in males and females
Operating the plasma display basic operations
Plasma concentrations were quantifiable in all the patients
Examples of using Kallikrein
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Plasma kallikrein binding proteins may be antibodies
Kb corresponding to StuI polymorphism of the kallikrein gene
Plasma kallikrein has been implicated in rheumatoid arthritis
