Examples of 'pleiotropic' in a sentence
Meaning of "pleiotropic"
Pleiotropic: a term used in genetics and biology to describe a gene or protein that has multiple effects on the phenotype, commonly used in scientific discussions in English
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- Of or pertaining to pleiotropy.
How to use "pleiotropic" in a sentence
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pleiotropic
May develop variants with pleiotropic effects.
Some pleiotropic effects can be investigated in the laboratory.
These genes are generally pleiotropic as well.
Pleiotropic effects of this drug are not entirely elucidated.
Fibrates have a pleiotropic mechanism of action.
Pleiotropic in nature and are involved in many biological processes.
All of these mutations are pleiotropic in expression.
The pleiotropic effect of scoC mutations was either positive or negative.
All such hybrids are particularly useful in developing pleiotropic molecules.
Hfq mediates its pleiotropic effects through several mechanisms.
The sponsors of the study were betting on the pleiotropic effects of pravastatin.
This cytokine has pleiotropic effects in immunoregulation and inflammation.
Such a gene that exhibits multiple phenotypic expression is called a pleiotropic gene.
B causing a pleiotropic regulatory response.
But we now proved that the constitutive mutation has a pleiotropic effect.
See also
It is a highly pleiotropic disorder.
It is a pleiotropic cytokine that is well known for inducing synthesis of various hepatic proteins.
Melatonin modulates a wide range of physiological functions with pleiotropic effects on the immune system.
Most cytokines are pleiotropic and express multiple biologically overlapping activities.
Other phenotypic effects are also envisaged because of the pleiotropic effect of the auxin hormone.
Relaxin initiates pleiotropic effects through multiple pathways on a variety of cell types.
It is obvious to the educated reader that Creatine acts as a pleiotropic nutritional supplement.
It should be emphasized that the pleiotropic actions are characterized by independent primary lipolytic action.
Pleiotropic genes affecting biosynthesis of antibiotics and differentiation in Streptomyces have been reported.
IFNγ is one of the most potent and pleiotropic cytokines of the immune system.
These pleiotropic effects play important roles during development and tissue regeneration.
Accumulating evidence indicates that TNF is a regulatory cytokine with pleiotropic biological activities.
Cytokines have pleiotropic effects and mediate a number of symptoms associated with inflammation.
Mice homozygous for a targeted mutation of the FX gene exhibit pleiotropic abnormalities including a lethal phenotype.
This pleiotropic resistance is one of the major obstacles to the successful treatment of tumors.
It binds to DNA sequences that contain certain motifs called pleiotropic drug response element PDRE.
These cytokines are pleiotropic and carry out many other functions of the immune response.
Vasoactive intestinal peptide: a neuropeptide with pleiotropic immune functions.
This cytokine will have a pleiotropic activity owing to the diversity of the targeted cell lines.
The effects of NF-kB are highly pleiotropic.
These cytokines have pleiotropic effects and mediate a wide range of symptoms associated with inflammation.
Interferons ( IFNs ) are a family of proteins which are pleiotropic effectors of the immune system.
One of the pleiotropic effects of the statins is the reduction in blood pressure BP.
Furthermore, modulators of neurotransmission exert pleiotropic effects on mental and cognitive functions.
LIF is a pleiotropic cytokine for which a function in pancreatic development has sofar not been described.
One reason, for this is the pleiotropic nature of many cytokines.
As a pleiotropic cytokine, it plays an important role in innate and adaptive immunity.
Resveratrol and quercetine are molecules with pleiotropic effects and leads to sirt1 activation.
As such pleiotropic mutations are undesirable, these mutants were considered to be less relevant.
In particular, variation in calcium-channel activity genes seems to have pleiotropic effects on psychopathology.
Modes of action and pleiotropic functions of Creatine compounds for cell and organ protection.
More in particular, the plant should preferably not show negative pleiotropic effects.
TGFa has pleiotropic biological effects.
However, modifying the physiologic effect of cytokines has been hindered due to their pleiotropic effects.
In this context, the pleiotropic effects of statins have lower relevance.
