Examples of 'ponatinib' in a sentence
Meaning of "ponatinib"
ponatinib (noun): A type of medication belonging to the class of tyrosine kinase inhibitors. It is used in the treatment of certain types of leukemia
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- An oral drug for the treatment of certain leukemias.
How to use "ponatinib" in a sentence
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ponatinib
The drug being tested in this study is ponatinib.
No human data on the effect of ponatinib on fertility are available.
Iclusig is a cancer medicine that contains the active substance ponatinib.
Substances that may increase ponatinib serum concentrations.
Substances that may have their serum concentrations altered by ponatinib.
Substances that may decrease ponatinib serum concentrations.
Importance of assessing the risks before starting treatment with ponatinib.
Intrinsic factors affecting ponatinib pharmacokinetics.
Ponatinib did not adversely affect important developmental parameters in the juvenile toxicity study.
Renal excretion is not a major route of ponatinib elimination.
It is unknown whether ponatinib affects the effectiveness of systemic hormonal contraceptives.
The active substance is ponatinib.
Ponatinib acts by blocking a tyrosine kinase called Bcr-Abl.
Close clinical surveillance is recommended when ponatinib is administered with these medicinal products.
At first I was in a clinical trial with ponatinib.
See also
Formal studies of ponatinib with anti-clotting medicinal products have not been conducted.
Second generation drugs that are currently marketed are nilotinib, dasatinib, bosutinib and ponatinib.
Recommendation to consider discontinuing ponatinib if a complete haematologic response has not occurred by 3 months 90 days.
In these patients, alternative treatment options should also be considered before starting treatment with ponatinib.
Gender, race and body weight were not predictive in explaining ponatinib pharmacokinetic intersubject variability.
Ponatinib is not displaced by concomitant administration of ibuprofen, nifedipine, propranolol, salicylic acid, or warfarin.
The blood / plasma ratio of ponatinib is.
Consider discontinuing ponatinib if a complete haematologic response has not occurred by 3 months 90 days.
The recommended starting dose is 45 mg of ponatinib once daily.
In vitro, ponatinib is an inhibitor of P-gp and BCRP.
Risk of blood clots from the use of the cancer medicine ponatinib (Iclusig®).
Ponatinib has been designed to be effective against these types of tumors . [ 3 ].
Examples of small molecule inhibitors of Bcr-Abl include but are not limited to ponatinib ( Iclusig ® ).
A total of 449 patients were treated with ponatinib at a starting dosage of 45 mg per day.
Ponatinib is metabolized by CYP3A4.
Bcr-Abl tyrosine-kinase inhibitor, especially the sections on Ponatinib development and binding.
Consider discontinuation of ponatinib in patients who develop serious heart failure see sections 4.2 and 4.8.
Each film-coated tablet contains 15 mg ponatinib as hydrochloride.
Ponatinib is the only TKI that can work against T315I mutant cells.
Each 15 mg film-coated tablet contains 15 mg ponatinib as ponatinib hydrochloride.
