Examples of 'poor solubility' in a sentence
Meaning of "poor solubility"
Poor solubility refers to the limited ability of a substance to dissolve in a particular solvent. This can be problematic in various fields, including pharmaceuticals, where it can affect the bioavailability and effectiveness of drugs
How to use "poor solubility" in a sentence
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poor solubility
Fenofibrate has very poor solubility in water.
Midostaurin is a compound with good absorption and poor solubility.
The compound has poor solubility in a number of organic solvents.
A common disadvantage of this group of drugs is their poor solubility.
The poor solubility and bioavailability of silibinin led to the enhanced formulations.
They can be used to carry drugs that have poor solubility.
The poor solubility in water of nifedipine in crystals causes in fact a low bioavailability.
The major limitation to the use of paclitaxel is its poor solubility.
The process is favoured by the relatively poor solubility of benzophenone in the solvent.
The poor solubility of drug is a significant problem in the design of pharmaceutical formulations.
Sterile filtration is not achievable due to the poor solubility of brinzolamide.
This poor solubility renders the urethane polymers unacceptable in automotive coating.
The resultant copolymers are of poor solubility in benzene and low isocyanate content.
In early experiments performed the polyol components were shown to exhibit poor solubility.
Due to poor solubility and absorption this medication will not affect fertility.
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These toxic side effects may be related to the poor solubility in water.
The poor solubility of these compounds in aqueous solution prohibits administration of effective doses.
All six formulations were emulsions with incomplete or poor solubility without effervescence.
Magnesium oxide has poor solubility in water and is poorly absorbed from the gut.
Hexamer or multimers having a higher molecular weight have a poor solubility in water.
Below the lower limit of surfactant poor solubility of wax in the composition is observed.
These polymers have a disadvantage in that they have relatively poor solubility in water.
Poor solubility in water gives low availability of the acetyl groups for peracetate formation.
However the obtained polyesters will have poor solubility and crystallization problems.
This poor solubility has somewhat limited the bioavailability of this preferred salt form.
Elemental sulfur is not efficient due to poor solubility and slow sulfurization reaction.
The poor solubility of minoxidil makes difficult to obtain topical formulations with good cosmeticity.
This hydrophobic portion may be responsible for the poor solubility of the protein.
Moreover poor solubility is usually associated to poor absorption in the body and poor availability.
Relatively little alcohol enters fat tissue due to its poor solubility in fat.
This material had poor solubility even after mixing and heating for an extended period.
The isolation of lithium from aqueous extracts of lithium ores capitalizes on this poor solubility.
Poor solubility and inadequate dissolution rate in the intestine result in lower absorption and bioavailability.
Dairy salt products of lower purity may have a bitter flavor and poor solubility.
PDI have poor solubility in monomers which generally have a lipophilic character.
Unsubstituted compounds according to the invention tend to have relatively poor solubility in aqueous solutions.
The crystals have poor solubility in various solvents, including oil.
The poorly soluble metal salts may also have poor solubility in their own right.
The poor solubility minimizes dye fading, thus providing a stable endpoint.
A further difficulty is the very poor solubility of cyclosporin A in water.
The molecules E and G were not included in this experiment due to their poor solubility.
This instability is due to poor solubility of Na-HEDP.
In particular the polyhydroxycarboxilic acid component ( iii ) has a poor solubility.
In particular, its very poor solubility in water is a problem.
Alternative concentrations may be used upon justification e.g. in case of cytotoxicity or poor solubility.
Preferably component c2 has poor solubility in the gastrointestinal lumen.
Nevertheless, the use of bixin is still limited by its poor solubility in water.
While at the same time, its poor solubility in water is mentioned as well.
Similar to NaDCC, but its use is limited due to its poor solubility.
However, they typically have poor solubility in aqueous solutions.
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They ate that poor woman alive
The poor thing has suffered a lot
Examples of using Solubility
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Solubility is increased by heat and mechanical agitation
In the same sequence solubility of samples changes
Solubility of a substance is useful when separating mixtures
