Examples of 'primary drying' in a sentence
Meaning of "primary drying"
primary drying: Primary drying is a process used in pharmaceutical or food industry to remove moisture from a product by sublimation, typically under vacuum conditions. It is an essential step in the production of certain freeze-dried products
How to use "primary drying" in a sentence
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primary drying
The length of primary drying was next evaluated.
The next step is the primary drying.
Primary drying is dependent on shelf temperature and pressure.
Following freezing there is a primary drying step.
Primary drying is done to remove the bulk solvent vía sublimation.
Organic solvents are also removed during primary drying.
Primary drying was completed prior to the secondary drying ramp.
The temperature is slowly increased during primary drying.
The primary drying stage was followed by a secondary drying stage.
Methods for determining the end point of primary drying.
Primary drying can also be performed using a temperature ramp.
An optional step after freezing and before primary drying is annealing.
This primary drying process is followed by the secondary drying stage.
This step of the lyophilization process is sometimes referred to as primary drying.
Primary drying and secondary drying are connected by a second temperature ramp.
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Temperature can be increased at the beginning or at the end of the primary drying.
The primary drying step may be followed by a secondary drying step.
This point indicates the end of the primary drying step in this invention.
Primary drying may also be mathematically modeled based on product temperature.
The temperature may remain constant during the whole primary drying process.
In the primary drying phase the water contained in the material is sublimated.
Product temperature during secondary drying is normally higher than during primary drying.
Primary drying can be performed at a constant temperature or a temperature ramp may be applied.
Alternatively the shelf temperature can be increased continuously during the primary drying.
This primary drying stage removes unbound moisture and acetic acid.
The drying phase can comprise a primary drying phase and a secondary drying phase.
In the primary drying step ice formed during freezing is removed by sublimation.
In that way all possibly existing ice that remained after primary drying was melted.
Primary drying time can be affected by the solids content in the formulation.
The pressure may be the same as that employed during the primary drying step.
The primary drying chamber has an internal flow space terminating in a discharge outlet.
This ensures that the entire solution is completely frozen before primary drying is started.
During primary drying water is removed under vacuum from the frozen dispersion.
This ensures that sublimation rather than melting will occur in the following primary drying stage.
During primary drying the water from the ice crystals that are formed is sublimated.
This ensures that sublimation rather than melting will occur in the following primary drying step.
The primary drying chamber and secondary apparatus can be integrated into a single unit.
Read more about Methods for determining the end point of primary drying.
This preferred primary drying cycle reduces the time necessary for the complete lyophilization process.
In one embodiment, drying comprises a primary drying step.
The conditions for primary drying can be determined empirically with lyophilization under different process parameters.
In one preferred embodiment, the methods include a two step primary drying.
Primary drying proceeds until the all of the crystalline ice has sublimed from the vials.
Method for monitoring primary drying of a freeze-drying process.
Preferably, unbound or easily removable ice is removed from the sample by the primary drying.
However, primary drying is typically the longest step in a lyophilization process.
Steps in freeze drying include pretreatment, freezing, primary drying and secondary drying.
In the primary drying step, the solvent is evaporated to obtain a syrup.
The method comprise two major steps, primary drying and stability drying.
Benefit, more process control, more homogenious end product properties and often faster primary drying.
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