Examples of 'procollagen' in a sentence
Meaning of "procollagen"
Procollagen is a precursor of collagen, a fibrous protein found in the connective tissues of the body. It is important for the structure and tensile strength of tissues like skin, tendons, and bones
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- The precursor of collagen; it is formed in fibroblasts and converted to collagen by a peptidase.
How to use "procollagen" in a sentence
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procollagen
Preferably said procollagen comprises monomeric procollagen.
Fibroblasts secrete a monomer called procollagen.
Preferably the procollagen is produced in plant cells.
The gel was cut to isolate the procollagen bands.
Preferably said procollagen is degradable by collagenase.
The signal peptide is cleaved off producing a procollagen molecule.
These procollagen molecules must be processed by enzymes in the cell.
The milk comprises procollagen or collagen.
Procollagen can not be processed correctly without this enzyme.
Note the reduction in procollagen secretion caused by benzoic hydrazide.
The mutations cause a decrease in secretion of trimeric procollagen molecules.
Conversion of procollagen to collagen can be completed by addition of proteases to the procollagen.
The invention further provides transgenes for expressing procollagen or collagen.
The trimeric portion of a procollagen triple helix is relatively resistant to proteases.
Some transgenic mammals express more than one procollagen gene.
See also
Recombinant procollagen or collagen.
The procollagen of the disclosure may be included in biodegradable acellular matrix components.
The method comprising providing procollagen preparation and purifying the procollagen.
Cleavage reactions can be performed before or after purification of procollagen from milk.
The procollagen molecule is secreted into the extracellular matrix where it forms fibrils.
Such dressings may be incorporated with the procollagen of the present invention.
Osteocalcin and procollagen peptides are also associated with bone formation and bone metastases.
Such a product is also envisaged to be incorporated with the procollagen of the present disclosure.
The amount of procollagen peptide in the conditioned medium was calculated from the standard curve.
Several types of laser affect fibroblast proliferation and synthesis of procollagen and collagen in vitro.
Each procollagen molecule assembles within the rough endoplasmic reticulum from its three constituent polypeptide chains.
Transgenic adult female mammals produce milk containing high concentrations of exogenous procollagen or collagen.
The conditioned media were collected and the procollagen contents were determined using a procollagen assay kit.
Procollagen molecules are needed to produce mature type II collagen.
The propeptides have a role in promoting interchain assembly of procollagen chains into triplex structures.
Procollagen III is a primary indicator used to determine the rate of collagen syn.
Transgenic mice exhibiting systemic expression of mutated forms of procollagen genes have also been reported.
The type II procollagen appeared in the void volume of the ion exchange column.
This indicates that propeptide of type III procollagen is absent.
Type I collagen is synthesized as a procollagen containing propeptide extensions at both ends of the molecule.
A series of clones were obtained that synthesized mRNA for human type II procollagen.
It can determine an increase of procollagen type III aminoterminal peptide.
The kit may comprise an antibody specific to carboxyterminal propeptide of type I procollagen and a label.
Procollagen I is a precursor of collagen.
The present invention relates to a method of measuring type I procollagen synthesis in humans.
Incorporation of procollagen into collagen-based matrices.
Controls were normal mouse milk spiked with different concentration of human type I procollagen homotrimer.
A method for synthesizing procollagen or collagen in cells comprising,.
The combination exhibits a synergistic effect on the synthesis of procollagen I.
Procollagen is susceptible to degradation by collagenases, including matrix metalloproteinases.
Thus the assay described previously is not specific for type I procollagen.
Usually, the exogenous procollagen or collagen is secreted in trimeric form.
Method for the immunological determination of the carboxyterminal propeptide of type I procollagen.
Following cultivation of such plants, the procollagen is typically harvested.
Procollagen still has unwound ends, which will be later trimmed.
