Examples of 'protein aggregates' in a sentence

Meaning of "protein aggregates"

protein aggregates: Protein aggregates are clumps of misfolded proteins that can accumulate in cells and disrupt normal cellular processes. They are commonly associated with neurodegenerative diseases like Alzheimer's and Parkinson's

How to use "protein aggregates" in a sentence

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protein aggregates
These protein aggregates are thought to be toxic to neurons.
An amyloid is any of certain insoluble fibrous protein aggregates.
These protein aggregates are often correlated with diseases.
Many neurodegenerative diseases show unusual protein aggregates.
The toxicity of protein aggregates in several neurodegenerative diseases.
Proteomics analysis revealed the composition of toxic protein aggregates.
The protein aggregates thus obtained are used in food application.
Such techniques also separate out various protein aggregates.
Very few protein aggregates were present using this technique.
Cationic surfactants have been used for solubilizing protein aggregates.
The formation of protein aggregates was analysed by electron microscopy by negative staining.
Membrane with sulfonic groups for removing protein aggregates.
Protein aggregates to water.
Cells have mechanisms that can refold or degrade protein aggregates.
Most of the protein aggregates in yeast cells get refolded by molecular chaperones.

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This approach has the serious problem of generating protein aggregates.
Clearance of protein aggregates and prion particles is however poorly understood and documented.
For industrial application it is desirable to eliminate or minimize the formation of protein aggregates.
Protein aggregates of high molecular weight were absent in all of the purified protein preparations.
Proteomic analysis of the ubiquitin system to study protein aggregates induced by proteasome inhibition.
The protein aggregates in the aqueous solution comprise at least one denatured globular protein.
It was not known in the prior art that PrPc forms large protein aggregates.
A current hypothesis assumes that the protein aggregates or the aggregation process itself is neurotoxic.
Protein containing frozen confectionery products have a tendency to aggregate to form protein aggregates or clots.
Pinpointing the source and possible resolution of protein aggregates is a promising direction for potential therapeutics.
The solubilized protein may accordingly be provided from a source of insoluble protein including protein aggregates.
Previous studies have shown that these protein aggregates can enter and harm cells.
Protein aggregates localize at JUNQ when they are ubiquitinated and targeted for degradation.
This provides a natural selection mechanism for reducing protein aggregates in the bacterial population.
These toxic protein aggregates are often referred to as Lewy bodies.
The UF permeate preferably has a low content of protein aggregates.
Larger molecular weight protein aggregates are visible when the gel is developed using Western blotting.
The mutant AAT protein may result in the formation of protein aggregates.
These techniques typically remove protein aggregates after the Protein A step.
If the protein aggregates are removed, the disease is in principle cured.
It enables us to obtain information on sub-micron protein aggregates.
How can we remove toxic protein aggregates or prevent their formation?
In human cells, many neurodegenerative disorders are characterized by abnormal protein aggregates.
Figure 3 also shows protein aggregates between small fat droplets.
In general the results of this activity are high-molecular weight protein aggregates.
The term " amyloid fibrils " means protein aggregates sharing specific structural traits.
This method is especially useful in cell-to-cell propagation of infectious cytosolic protein aggregates.
The diameter of the protein aggregates may be measured by, for example, light scattering techniques.
In particular, researchers concentrated on the association of protein aggregates with cellular membranes.
To isolate these inactive protein aggregates ( inclusion bodies ), the prokaryotic cells are disrupted following fermentation.
As ferritin accumulates within cells of the reticuloendothelial system, protein aggregates are formed as hemosiderin.
Intracellular protein aggregates also occur in other neurodegenerative diseases, for example Alzheimer 's disease.
In addition, many neurodegenerative diseases are characterized by protein aggregates very similar to stress granules.
When mixing at pH 5.3, the protein aggregates can inhibit the protein binding with the polysaccharide.
Apparently, some of the guar gum was trapped in the protein aggregates during autoclaving.

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