Examples of 'protein bound' in a sentence
Meaning of "protein bound"
The term protein bound is used in biochemistry and pharmacology to describe a situation where a drug or substance in the blood stream becomes bound or attached to proteins, such as albumin. This binding can affect the distribution, metabolism, and elimination of the substance, and can impact its overall effectiveness and duration of action in the body
How to use "protein bound" in a sentence
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protein bound
Recovering the target protein bound to said aptamer.
Protein bound radioactivity was determined using a gamma or scintillation counter.
Ambrisentan is highly plasma protein bound.
Rosiglitazone is highly protein bound and is not cleared by haemodialysis.
Haemodialysis is unlikely to be beneficial given that lomitapide is highly protein bound.
No interaction with highly protein bound compounds is therefore expected.
They inhibit FXa with high picomolar affinity and are highly protein bound in plasma.
Plasma protein bound.
Care should be exercised when administering torasemide with other highly plasma protein bound drugs.
Percent protein bound in rat and human plasma is also measured.
It is highly protein bound.
Lorazepam is highly protein bound and is extensively metabolized into pharmacologically inactive metabolites.
It also helps to remove some of the protein bound to the mineral.
The fusión protein bound to the immobilized ligand may be detected in a variety of ways.
These measures included total free and protein bound ceftriaxone and calcium.
See also
The cytotoxic protein bound the target biomolecule of its scFv binding region.
The sample may be treated to separate the free from the protein bound active ingredients.
Nicardipine is highly protein bound in human plasma over a wide concentration range.
HIV protease inhibitors may be protein bound.
Esomeprazole is extensively plasma protein bound and is therefore not readily dialysable.
The resin beads bind released drug, whether free or protein bound.
One flow cell with no immobilized protein bound to it was used as a background control.
In a preferred embodiment, cobalt was selected to react with protein bound thiol groups.
Optimizing clearance for protein bound molecules using cascade filtration therapy.
One RU represents approximately one picogram of protein bound to the surface.
Estrogens are plasma protein bound to albumin and / or sex hormone-binding globulin in the circulation.
The interaction between duloxetine and other highly protein bound drug has not been fully evaluated.
Protein bound to the aptamer produced unique ionic current signatures, which facilitated accurate target recognition.
Leflunomide and its metabolites are extensively protein bound and undergo further metabolism before excretion.
ISMN has a volume of distribution of about 40 litres and is not significantly protein bound.
A small amount is not protein bound and is called free PSA.
Approximately 35 % of the barbiturate in blood is plasma protein bound.
A heparan sulfate-binding protein bound to a solid phase.
Activin B protein bound the plates in a dose-dependent manner.
That antibody binds the Flag sequence of the ArsR protein bound to the DNA.
Proteoglycans contain a core protein bound covalently to at least one chain of glycosaminoglycan ( GAG ).
In a further alternative, an affinity column comprises a hek / Fc fusión protein bound to a Protein A column.
It is less than 5 % protein bound and is excreted unchanged in the urine.
Also, the new compounds are not as highly serum protein bound as other glycopeptides.
Riluzole is about 97 % protein bound and it binds mainly to serum albumin and to lipoproteins.
Unbound eltrombopag ( active ) concentrations for this highly protein bound medicinal product were not measured.
Diazepam is highly protein bound with 96 to 99 percent of the absorbed drug being protein bound.
Cointroduced RARs can dimerize with such a fusión protein bound to the cis-regulatory element.
The drug distributes uniformly in most body fluids and is approximately 25 % protein bound.
Several anticonvulsants are highly protein bound and in certain situations e . g.
These antibodies, can also be used to effectively co-precipitate and isolate a protein bound to caspase-8.
Furthermore, parathyroid hormone is not protein bound and has a low volume of distribution.
Distribution Nitroglycerin and its major metabolites are approximately 60 % protein bound.
The pump consists of a single protein bound to a Vitamin A derivative, retinal.
The protein bound to each column was then eluted in a single step with 1.0 M NaCl-Acetate buffer.
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Examples of using Bound
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Folks are bound to ship cotton down river
Able to leap tall buildings in a single bound
She was bound to come out one day
