Examples of 'protein tyrosine kinase' in a sentence
Meaning of "protein tyrosine kinase"
Protein tyrosine kinase: This phrase refers to a type of enzyme that plays a role in cell signaling and communication, particularly in the process of transferring phosphate groups to proteins
How to use "protein tyrosine kinase" in a sentence
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protein tyrosine kinase
The compounds of the invention are inhibitors of protein tyrosine kinase activity.
The Src protein tyrosine kinase plays a role in osteoporosis and other bone diseases.
Evaluated have no documented estrogenic or protein tyrosine kinase inhibitory activity.
An example of protein tyrosine kinases is a Group VII protein tyrosine kinase.
Numerous oncogenic viruses appear to operate by encoding a protein tyrosine kinase.
Our Protein Tyrosine Kinase products is good in quality and competitive in price.
The EGF receptor is a transmembrane protein tyrosine kinase.
In another embodiment the protein tyrosine kinase is a Group XIV protein tyrosine kinase.
Field of the Invention This invention relates to compounds that inhibit protein tyrosine kinase activity.
Typically, a protein tyrosine kinase is used.
RET encodes a transmembrane receptor of the protein tyrosine kinase family.
Genistein, a braod range protein tyrosine kinase inhibitor, inhibited the phosphorylation of these serines.
Test for activity against c-Abl protein tyrosine kinase.
The fusión gene has a protein tyrosine kinase domain together with a coiled-coil domain.
In another embodiment the one or more protein kinase ( s ) is a protein tyrosine kinase.
See also
In certain embodiments, the protein tyrosine kinase is a non-receptor tyrosine kinase.
In one aspect of the invention, the protein kinase is a protein tyrosine kinase.
PDGF-D interacts with a protein tyrosine kinase growth factor receptor.
In particular, the invention relates to quinazoline derivatives which exhibit protein tyrosine kinase inhibition.
VEGF-D will interact with protein tyrosine kinase growth factor receptors.
In particular, the invention relates to a quinazoline derivative which exhibits protein tyrosine kinase inhibition.
BTK kinase is a cytoplasmic protein tyrosine kinase crucial for B-cell development and differentiation.
In addition, the following documents show the antitumor activity of protein tyrosine kinase inhibitors.
ABL1 The protein tyrosine kinase c-Abl shuttles between the nuclear and cytoplasmic compartments.
CMet is a member of the class IV protein tyrosine kinase receptor family.
The method includes wherein the protein kinase is a protein serine / threonine kinase or a protein tyrosine kinase.
Finally, it is known that radicicol has a protein tyrosine kinase inhibiting activity.
The use includes wherein the protein kinase is a protein serine / threonine kinase or a protein tyrosine kinase.
Focal adhesion kinase ( FAK ) is a cytoplasmic protein tyrosine kinase that is localized to focal adhesions.
In one embodiment, the PK related disorder is a disorder related to receptor protein tyrosine kinase.
A Group XIV protein tyrosine kinase of particular interest is FLT3.
In another preferred embodiment, the protein tyrosine kinase in PDGFr.
The compounds of Formula I are especially potent inhibitors of the c-fms protein tyrosine kinase.
Additional instances of factor-influenced protein tyrosine kinase activity, similar to this one, exist.
Thus, a need exists for selective and potent small-molecule protein tyrosine kinase inhibitors.
Lymphocyte-specific protein tyrosine kinase ( LCK ) served as a negative control.
The active substance in Iressa, gefitinib, is a protein tyrosine kinase inhibitor.
An example of a receptor protein tyrosine kinase is the HGF receptor, particularly the HGF / c-Met receptor.
The active substance in Gefitinib Mylan, gefitinib, is a protein tyrosine kinase inhibitor.
HER4/Erb4 is a receptor protein tyrosine kinase belonging to the ErbB family.
Moreover, the intracellular part of TF is not endowed with intrinsic protein tyrosine kinase activity.
C-Abl is a ubiquitously expressed protein tyrosine kinase with the approximate molecular weight of 145 kDa.
One group of receptors relevant to this invention possess intrinsic protein tyrosine kinase ( PTK ) activity.
The protein kinase can be, for example, a protein tyrosine kinase or a protein serine / threonine kinase.
The c-erbB-2 growth factor receptor protein, a protein of the membrane receptor protein tyrosine kinase family A.
Use of Claim 22 wherein the protein tyrosine kinase is c-Src, PDGFR or FGFR.
The use of claim 23 wherein the protein kinase is a protein tyrosine kinase.
For example, the compound can be a protein tyrosine kinase ( PTK ) inhibitor.
Abbreviations and Definitions " rPTK " means a receptor protein tyrosine kinase.
In another preferred embodiment, the protein tyrosine kinase is FGFr.
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