Examples of 'proteolytic cleavage site' in a sentence
Meaning of "proteolytic cleavage site"
Proteolytic cleavage site: A specific location on a protein where proteases can cleave the peptide bonds. This process is important for protein activation, degradation, and regulation in various biological pathways
How to use "proteolytic cleavage site" in a sentence
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proteolytic cleavage site
The linker polypeptide sequence may also contain a proteolytic cleavage site.
Eliminating this proteolytic cleavage site improves drug efficacy by increasing exposure to active drug.
The two amino acids in bold indicate the proteolytic cleavage site.
Eliminating this proteolytic cleavage site may improve drug efficacy by increasing exposure to active drug.
Suitably the target polypeptide comprises at least one such proteolytic cleavage site.
The proteolytic cleavage site was introduced with a proteolytic cleavage sequence derived from the insulin receptor.
Another universal numbering system also used refers to the proteolytic cleavage site.
Y is the MMP proteolytic cleavage site.
Such a hydrophilic region may facilitate cleavage by an enzyme at the proteolytic cleavage site.
Thus, for example, a proteolytic cleavage site may be used for cleavage by proteases.
In certain embodiments, the linker can comprise a nucleotide sequence encoding a proteolytic cleavage site.
N-terminal residues derived from proteolytic cleavage site of the GST-fusion protein are between brackets.
Accordingly, the intergenic region can include a nucleotide sequence encoding a proteolytic cleavage site.
Preferably the MMP proteolytic cleavage site comprises 8 amino acids.
In certain embodiments, the intergenic region can comprise a nucleotide sequence coding for a proteolytic cleavage site.
See also
Method according to claim 3, wherein the specific proteolytic cleavage site is an enzymatic cleavage site.
The proteolytic cleavage site is a matrix metalloproteinase ( MMP ) cleavage site.
Preferably, the DNA sequence coding for a proteolytic cleavage site is read on the fragment b.
The MMP proteolytic cleavage site may comprise the amino acid sequence ( i ).
Furthermore, such DNA sequence coding for a linker may a proteolytic cleavage site for the expressed protein.
In a preferred embodiment the MMP proteolytic cleavage site comprises the amino acid sequence ( iv ).
Y is a matrix metalloproteinase ( MMP ) proteolytic cleavage site.
Y comprises a matrix metalloproteinase ( MMP ) proteolytic cleavage site.
Y comprises the matrix metalloproteinase ( MMP ) proteolytic cleavage site.
The nucleic acid molecule of claim 1 wherein the proteolytic cleavage site is SEQ ID NO, 29.
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