Examples of 'protooncogene' in a sentence

Meaning of "protooncogene"

protooncogene (noun) - A protooncogene is a gene that can be transformed into an oncogene (a gene that has the potential to cause cancer) due to mutations or increased expression
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  • Alternative form of proto-oncogene.

How to use "protooncogene" in a sentence

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protooncogene
The neu protooncogene is notably amplified in patients with metastatic breast cancer.
Thus, this normal cellular gene is identified as a protooncogene.
This suggests that the protooncogene of the present invention induces cervical cancer.
As a result of this translocation, transcription of the protooncogene c-myc is activated.
The met protooncogene protein is a member of the tyrosine kinase growth factor receptor family.
This gene may be a eukaryotic gene, a viral gene, an oncogene or a protooncogene.
Protooncogene expression was analyzed by the Northern hybridization.
A kit for diagnosing cancer which comprises the protooncogene or fragment of claim 1 or 2.
The neu protooncogene has been identified in ethylnitrosourea-induced rat neuroblastomas.
Another embodiment of a genetically engineered construct derives from the c - jun protooncogene and related genes.
A vector comprising the protooncogene or a biologically active fragment of claim 1.
The receptor for M-CSF is a cell surface tyrosine kinase receptor, encoded by the protooncogene cfms.
This suggests that the protooncogene of the present invention is a membrane-bound gene.
Important examples are the mutational activation of the protooncogene c-Ha-ras.
Akt is the human homologue of the protooncogene v-akt of the acutely transforming retrovirus AKT8.

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Figure 2 shows the tissue expression of c-Met protooncogene ( MET ).
As a consequence the ABL protooncogene on chromosome 9 is fused to the BCR gene on chromosome 22.
A kit for diagnosis of cancer which comprises the protooncogene of claim 1 or 2.
A human cervical cancer 2 protooncogene having the nucleic acid sequence of SEQ ID NO, 1.
A vector comprising the protooncogene of claim 1 or 2.
This suggests that HCCR-1 protooncogene enhances the cellular PKC activity.
Moreover, its cellular homolog, the protooncogene pp60c-src transmits oncogenic signals of many receptors.

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