Examples of 'pyrazinyl' in a sentence
Meaning of "pyrazinyl"
Pyrazinyl is a chemical term used to describe an organic compound containing the pyrazine ring structure
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- The radical derived from pyrazine.
How to use "pyrazinyl" in a sentence
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pyrazinyl
Preferred heteroaryl groups are pyridyl and pyrazinyl.
Pyrazinyl methyl sulfide.
A preferred heteroaryl group is pyrazinyl.
Generally, pyrazinyl compounds are preferred over pyridyl compounds.
Ar is an optionally further substituted phenyl, pyridinyl, pyrimidinyl or pyrazinyl.
Pyrazinyl substituted with trifluoromethyl, or.
The heterocyclic group is a pyridyl, pyrazinyl and pyrimidinyl.
Suitable heteroaryl groups include pyridinyl, pyrimidinyl, pyridazinyl and pyrazinyl.
Preferred heteroaryl rings are pyridinyl, thiophenyl and pyrazinyl which are optionally substituted with alkyl.
Exemplary heteroaralkenyl groups may contain thienyl, pyridyl, imidazolyl and pyrazinyl.
Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors.
Preferred heteroaryl groups are pyridinyl, pyrimidinyl, pyrazinyl or quinolinyl.
The pyrazinyl group may include 2-pyrazinyl.
Examples of the heterocyclic group include pyridyl, pyrazinyl and pyrimidinyl.
Represents a phenyl, pyridyl, pyrazinyl or quinolinyl group ; R 6 represents a halogen atom ;.
See also
Examples of hetAr1 include unsubstituted or substituted pyridyl, pyrazinyl and pyridazinyl groups.
In another embodiment, Ar1 is a pyrazinyl group, m is 0, and Ar2 is a benzoimidazolyl group.
Examples for heteroaryl moieties include but are not limited to pyridinyl, pyrimidinyl, or pyrazinyl.
In another preferred aspect of the invention, Ar1 is pyrazinyl or substituted pyrazinyl.
Examples of monocyclic heteroaryl with 6 members are pyridyl, pyrimidinyl, pyridazinyl or pyrazinyl.
Pyridyl, pyridazinyl, pyrimidinyl, and pyrazinyl are more preferable.
In a still further embodiment, Rd represents optionally substituted pyrazinyl.
Of these, the pyridyl, imidazolyl, oxazolyl, pyrazinyl and thiazolyl groups are more preferred.
Particular heteroaryl groups are selected from the group consisting of pyridyl, pyrazinyl and pyrimidinyl.
Examples of heteroaromatic rings R4 are pyridinyl, pyrazinyl and thiazolyl, optionally substituted as defined above.
The diazine ring may be selected from the group consisting of pyrimidinyl, pyrazinyl and pyridazinyl.
Specific examples of such unsubstituted and substituted pyrazinyl groups include the 2-pyrazinyl and 2-methoxy-5-pyrazinyl groups.
In one embodiment, Ar is optionally substituted pyrazinyl.
In another aspect, Ar1 is a pyrazinyl group and p is 1.
More preferably, at least one I group is pyridyl or pyrazinyl.
In another embodiment, Ar1 is a pyrazinyl group and p is 1.
Disclosed herein is a compound of formula I wherein Ar1 is pyrazinyl.
In some embodiments, ring A is pyrazinyl substituted with halo, e.g., chloro or fluoro.
RA is preferably a pyridyl, pyrimidinyl or pyrazinyl group.
In some embodiments, ring A is pyrazinyl optionally substituted with halo or -C1-C4 haloalkyl.
In one or more embodiments of the present invention A represents pyridyl, pyrazinyl or quinolyl.
Or, At is an optionally substituted pyrazinyl or triazinyl.
Preferred 5 to 6 membered heteroaryl groups include pyrazolyl, imidazolyl, pyridinyl, pyrimidinyl or pyrazinyl.
Preferably, Het is pyridinyl, pyrazinyl or indolyl.
Examples of 6 membered ring heteroaryl are pyridyl, pyrimidinyl, pyridazinyl, and pyrazinyl.
A compound of claim 1 wherein Het is pyrazinyl or 5-pyrimidinyl.
In still another embodiment, the " monocyclic nitrogen-containing heteroaryl " is pyrazinyl.
In another embodiment R1 represents unsubstituted pyrazinyl or pyrimidinyl.
Preferred heteroaryl groups are pyridyl, pyridazinyl, pyrmidinyl and pyrazinyl.
In another embodiment, Ar1 is a pyrazinyl group.
Examples of 6-membered monocyclic heteroaryl groups are pyridinyl, pyridazinyl, pyrimidinyl and pyrazinyl.
Typical 6-membered heteroaryl groups are pyridyl, pyrimidinyl, pyrazinyl and pyridazinyl.
Examples of 6-membered heteroaromatic groups include pyridyl, triazinyl, pyridazinyl, pyrimidinyl and pyrazinyl.
Or, A1 is an optionally substituted pyrazinyl or triazinyl.
Among the preferred values of A are phenyl, naphthyl, pyridyl, piperazinyl, pyrimidinyl, pyridazinyl and pyrazinyl.
