Examples of 'pyrazoles' in a sentence
Meaning of "pyrazoles"
Pyrazoles are a class of organic compounds containing a 5-membered aromatic ring made up of three carbon atoms and two nitrogen atoms. They are often used in pharmaceuticals and agrochemicals
Show more definitions
- plural of pyrazole
How to use "pyrazoles" in a sentence
Basic
Advanced
pyrazoles
Certain bicyclic pyrazoles have been previously described.
Hydrazine reacts to produce pyrazoles source.
Various pyrazoles have previously been described.
Hydrazine reacts to produce pyrazoles more.
Pyrazoles have been described for use in the treatment of inflammation.
The nitration of pyrazoles is well known.
An important class of fungicides are the pyrazoles.
Some of these pyrazoles have been reported to have pharmacological activity.
Process for preparing pyrazoles.
Some of those pyrazoles have been reported to have pharmacological activity.
These processes are therefore unsuitable for large scale production of substituted pyrazoles.
The salts of the above pyrazoles are an additional aspect of the invention.
Pyrazoles can be readily synthesized by the reaction of diazomethane with acetylene.
Appropriate fractions were evaporated and dried in vacuo to give the final pyrazoles.
Pyrazoles react with potassium borohydride to form a class of ligands known as scorpionate.
See also
Often these applications involve conversion of hydrazine to heterocyclic rings such as pyrazoles and pyridazines.
Discloses phenyl pyrazoles as endothelin receptor antagonists for treating cardiovascular or renal disease.
The pyrazoline compounds could be oxidized into their corresponding pyrazoles XXXXV under oxidative conditions.
Suitable pyrazoles for use to prepare compounds of the invention also may be readily synthesized.
A method of preparing pyrazoles of Formula LA wherein.
Such pyrazoles have been indicated as having pharmaceutical activity including hypoglycemic activity and antiinflammatory activity.
Other preferred phenyl pyrazoles include the following compounds,.
Sequential treatment with dimethoxymethyl-dimethyl amine and a hydrazine provides the heterocyclic pyrazoles.
Also teaches novel pyrazoles useful for inhibiting HIV reverse transcriptase.
Other preferred blocking agents include lactams, secondary and tertiary alcohols, pyrazoles and their mixtures.
Substituted pyrazoles as IRAK inhibitors.
Pyrazoles are five-membered nitrogen containing heterocycles, whose derivatives can be widely used in medicinal chemistry.
Examples of suitable diaryl substituted pyrazoles for use in the compositions include celecoxib, rofecoxib.
These pyrazoles are effective in inhibiting human sPLA2 mediated release of fatty acids.
A second preferred synthetic method for obtaining pyrazoles of the present invention is described in scheme 6.
The present invention relates to N-alkylation of substituted pyrazoles.
The following pyrazoles were used as starting materials,.
Moreover, the present invention relates to a method of preparing pyrazoles of Formula LA, wherein.
For instance, substituted pyrazoles suitable as starting reagents are commercially available.
Synthetic Scheme III shows a regioselective preparation of substituted pyrazoles 4 of the present invention from ketones 9.
The following pyrazoles could be prepared by the procedures described above,.
Table 1D, Comparison of nematicidal oxadiazoles with nematicidal pyrazoles and thiazoles.
In the synthesis of the pyrazoles and pyrroles, reactions were facilitated by microwave irradiation.
Other preferred compounds of the invention also include pyrazoles of formula ID, Wherein.
A class of substituted pyrazoles of particular interest consists of those compounds having the formula, wherein.
Scheme III outlines the formation of pyrazoles for use in scheme I-II.
Pyrazoles C7 can be transformed further into final compounds as described in the Schemes above.
Scheme 23 describes the general synthesis for pyrazoles which have thio and oxidized sulfur derivatives.
Table 1D, Comparison of nematicidal oxazoles and oxadiazoles with nematicidal pyrazoles and thiazoles.
Such substituted pyrazoles can be prepared as shown in Scheme 5.
Synthetic Scheme I illustrates the procedure used to prepare the anti-inflammatory pyrazoles of the present invention.
The synthesis of pyrazoles of Formula I can be prepared as shown in Schemes 1 and 2.
Scheme IV outlines the formation of pyrazoles for use in scheme I-III.
Typical blocking agents are alcohols, ketimines, oximes, and pyrazoles.
However, Alkylation of unsymmetrically substituted pyrazoles usually proceeds with formation of two regioisomers.
