Examples of 'pyrimidinyl' in a sentence
Meaning of "pyrimidinyl"
pyrimidinyl - This term does not have a commonly recognized definition in English. It might be a specialized term or a scientific term
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- A univalent radical derived from pyrimidine
How to use "pyrimidinyl" in a sentence
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pyrimidinyl
More preferably the heteroaryl is pyrimidinyl or pyridyl.
Pyridyl and pyrimidinyl are particularly preferable.
Examples may include pyridinyl and pyrimidinyl.
A preferred heteroaryl group is pyrimidinyl optionally substituted with methyl.
G is an unsubstituted or substituted or fused pyrimidinyl group.
The pyrimidinyl organophosphorous compound can be recovered by conventional means.
The compounds do not bear a pyrimidinyl group.
The pyrimidinyl or triazinyl group may also be substituted in some embodiments.
Preferred heteroaryl groups are pyridyl and pyrimidinyl groups.
Suitably Ra is pyridinyl or pyrimidinyl optionally substituted with one trifluoromethyl.
Exemplary heteroaryl groups in this embodiment are pyridinyl and pyrimidinyl.
Phenyl, pyridyl and pyrimidinyl are more preferred.
Z preferably denotes pyridinyl or pyrimidinyl.
Pyrimidinyl group optionally substituted by one or two pyrrolidinyl groups, or.
Is optionally substituted pyrimidinyl.
See also
R1 preferably is a pyridinyl or pyrimidinyl moiety optionally substituted as defined above.
Suitably Ra is optionally substituted pyridinyl or optionally substituted pyrimidinyl.
R ² is preferably pyridinyl and pyrimidinyl and more preferably pyridinyl.
In one aspect of the invention A is pyridyl or pyrimidinyl.
Is preferably pyridinyl and pyrimidinyl and benzodioxolyl ; more preferably pyridinyl.
In the compounds according to formula I G is an unsubstituted or substituted pyrimidinyl group.
A compound according to claim 4 wherein the pyrimidinyl or pyridinyl is substituted with halogen.
The heterocyclic group is a pyridyl, pyrazinyl and pyrimidinyl.
Preferred as substitutents for pyridinyl and pyrimidinyl are halogen, cyano and nitro, especially chlorine.
A particular value for heteroaryl is furyl, pyridyl or pyrimidinyl.
The process according to claim 4, wherein the pyridyl or pyrimidinyl group is substituted with trifluoromethyl.
Ar is an optionally substituted ring selected from phenyl, pyridyl, or pyrimidinyl.
Where the compound contains a pyridyl or pyrimidinyl group, it may be salified.
Examples of the heterocyclic group include pyridyl, pyrazinyl and pyrimidinyl.
RA is preferably a pyridyl, pyrimidinyl or pyrazinyl group.
Nitrogen-containing groups are especially useful, particularly pyridyl or pyrimidinyl groups.
Preferably, A is selected from the group consisting of pyrimidinyl, pyridinyl and triazolyl, more preferably pyrimidinyl.
The process according to claim 2, wherein the heterocyclic group is a pyridyl or pyrimidinyl group.
Suitably R6 is pyrimidinyl optionally substituted with one substituent.
A preferred heteroaryl group is pyridinyl, pyrimidinyl or benzdioxolanyl.
Particular heteroaryl groups are selected from the group consisting of pyridyl, pyrazinyl and pyrimidinyl.
The most preferred het are pyridyl, pyrimidinyl and thiazolyl.
In a first particular aspect of that embodiment, R1 represents optionally substituted pyrimidinyl.
In another embodiment, pyrimidinyl group.
Preferred azaheteroaryl groups within R1 include optionally substituted pyridyl and pyrimidinyl.
In another preferred aspect of the invention, Ar1 is pyrimidinyl or substituted pyrimidinyl.
Preferred azaheteroaryl groups for R1 and R2 include optionally substituted pyridyl and pyrimidinyl.
Suitably, Y represents optionally substituted pyrimidinyl or optionally substituted purinyl.
Particularly useful groups of these types include optionally substitued phenyl, pyridyl or pyrimidinyl groups.
Aminopyridazinyl ; pyrimidinyl optionally substituted with an amino group ;.
Ar is an optionally further substituted phenyl, pyridinyl, pyrimidinyl or pyrazinyl.
The pyridinyl, pyrrolyl, thienyl, furanyl, pyrimidinyl or triazolyl groups are more particularly concerned ;.
G is an unsubstituted or substituted pyrimidinyl group ;.
The pyrimidinyl 2 ' - deoxyribonucleoside starting compound of the reduction step is preferably a thymidine derivative.
Examples of such heteroaryl groups are pyridinyl, pyrazinyl, pyrimidinyl or pyridazinyl.