Examples of 'pyrrolidinyl' in a sentence
Meaning of "pyrrolidinyl"
pyrrolidinyl", "definition": "Pyrrolidinyl is a noun that describes a chemical compound containing a pyrrolidine ring structure.", "context": "The researchers synthesized a new pyrrolidinyl compound for testing.
Show more definitions
- A radical derived from pyrrolidine
How to use "pyrrolidinyl" in a sentence
Basic
Advanced
pyrrolidinyl
Particularly preferred is a pyrrolidinyl group or a morpholino group.
Further examples are azetidinyl and pyrrolidinyl.
Piperidyl and pyrrolidinyl moieties are especially preferred.
The heterocycle is preferably morpholino or pyrrolidinyl.
Examples include pyrrolidinyl and piperidinyl.
A preferred embodiment is where as a substituted monocyclic azaheterocyclyl is substituted pyrrolidinyl.
In one embodiment the pyrrolidinyl is substituted with oxo.
The pyrrolidinyl and piperidyl groups are advantageously substituted on the nitrogen atom.
Of particular interest is the pyrrolidinyl group.
Intermediates containing a pyrrolidinyl group bearing a nitrogenous radical are also disclosed herein.
Representative examples of an azacycloalkyl group are pyrrolidinyl and piperidinyl groups.
A preferred embodiment according to the invention is where as a substituted monocyclic azaheterocyclyl is substituted pyrrolidinyl.
It likewise pertains to intermediate compounds containing a pyrrolidinyl group bearing a nitrogenous radical.
Morpholino, pyrrolidinyl and piperazinyl groups are preferred.
Particularly preferred are Raloxifene and its pyrrolidinyl analog.
See also
This invention pertains to pyrrolidinyl compounds and methods for using the same.
Preferred heterocycloalkyl groups are morpholinyl, piperidinyl or pyrrolidinyl.
Or is pyrrolidinyl which can be substituted by benzyl ;.
In certain embodiments, the ring is pyrrolyl or pyrrolidinyl.
Is a pyrrolidinyl group optionally substituted by 1 to 5 substituents selected from.
In another embodiment, this heterocycloalkyl group is pyrrolidinyl.
Preferably, pyrrolidinyl group can be mentioned.
Compound of claim 1 wherein ring is pyrrolidinyl.
A is pyrrolidinyl azepanyl or piperidinyl ; and pharmaceutically acceptable salts and esters thereof.
Examples include piperidinyl, pyrrolidinyl and piperazinyl groups.
In some embodiments, the heterocyclyl is pyrrolidinyl.
Non-aromatic heterocyclic groups include pyrrolidinyl tetrahydrofuryl, tetrahydrothienyl and piperidinyl.
Preferred heterocyclyl groups are piperidinyl, morpholinyl and pyrrolidinyl.
The substitution site of - CORb on the pyrrolidinyl is not particularly limited.
Furthermore it can be tetrazolyl, piperidinyl or pyrrolidinyl.
Preferably, it is pyrrolidinyl group, piperidinyl group or morpholinyl group.
Pyrimidine optionally substituted by one or two pyrrolidinyl groups, or.
Of these, azetidinyl, pyrrolidinyl, morpholino and piperazinyl are preferred ; pyrrolidinyl is more preferred.
Most preferred are piperazinyl, tetrahydropyranyl, morpholinyl and pyrrolidinyl.
Examples of heterocycloalkyl groups are piperidinyl, piperazinyl, pyrrolidinyl and morpholinyl groups, and derivatives thereof.
In another embodiment, this heterocycloalkyl group is piperidinyl or pyrrolidinyl.
Examples of heterocycloalkyl groups are the piperidinyl, piperazinyl, pyrrolidinyl and morpholinyl groups and their derivatives.
Examples of heterocycloalkyl groups include morpholinyl, piperazinyl and pyrrolidinyl.
We prefer W to represent azetidinyl or pyrrolidinyl, especially pyrrolidinyl.
Another non-limiting example of heterocycloalkyl includes pyrrolidinyl.
Represents a pyrrolidinyl group ;.
The heterocycloalkyl is more particularly morpholinyl, piperazinyl, pyrrolidinyl or piperidyl.
Is a pyrrolidinyl group optionally substituted by 1 to 5 substituents selected from the group consisting of,.
Examples of saturated heterocycles are azetidinyl, pyrrolidinyl and piperidinyl.
Among them, preferred is a pyrrolidinyl group, a piperidino group, a morpholino group or a piperazino group.
Pyrimidinyl group optionally substituted by one or two pyrrolidinyl groups, or.
In one embodiment the pyrrolidinyl substituted with oxo is pyrrolidin-2-yl substituted with oxo.
In one embodiment, heterocyclyl is pyrrolidinyl.
Preferably, pyrrolidinyl group, piperidinyl group, piperazinyl group and morpholinyl group can be mentioned.
R6 may represent piperazinyl or pyrrolidinyl.
