Examples of 'recombinant adenoviruses' in a sentence
Meaning of "recombinant adenoviruses"
Recombinant adenoviruses: Are genetically modified adenoviruses created by combining DNA from different sources, frequently used in biotechnology and gene therapy for various research and medical purposes
How to use "recombinant adenoviruses" in a sentence
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recombinant adenoviruses
Immunohistology of cells infected with recombinant adenoviruses.
New recombinant adenoviruses as expression vectors for vaccine applications.
Preparation of the recombinant adenoviruses.
The recombinant adenoviruses thus generated are selected by purification on plates.
Several approaches traditionally have been used to generate the recombinant adenoviruses.
Recombinant adenoviruses as priming agent.
This suboptimal response can be corrected by genetic vaccination with recombinant adenoviruses.
The recombinant adenoviruses which were thereby generated were selected by plaque purification.
Such a helper baculovirus can thus be used to transcomplement minimum recombinant adenoviruses.
The recombinant adenoviruses according to the invention may be of various origins.
The digestion product is used directly for producing the recombinant adenoviruses.
Recombinant adenoviruses have been described for delivery of molecules to host cells.
The present invention relates to compositions and methods for preparing recombinant adenoviruses.
The defective recombinant adenoviruses according to the invention can be prepared in various ways.
This embodiment is particularly advantageous for the production of highly defective recombinant adenoviruses.
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The recombinant adenoviruses are usually produced in a cell line complementing the defective functions.
This system is most particularly advantageous for the production of defective recombinant adenoviruses.
The recombinant adenoviruses are capable of delivering a suitable gene to mammalian cells and tissues.
A variety of mammalian cell lines are publicly available for the culture of recombinant adenoviruses.
The invention provides recombinant adenoviruses that produce an oncolytic effect in a cancer cell.
Influence of cell-cycle inhibitor apigenin on luciferase expression from recombinant adenoviruses.
Infection of HeLa cells by these recombinant adenoviruses allows for diminished endogenous target gene expression.
Thus, the present invention describes novel tools and novel methods for constructing recombinant adenoviruses.
Recombinant Adenoviruses comprising simian adenovirus proteins and uses thereof.
Furthermore, the construction of defective recombinant adenoviruses has also been described in the literature.
The recombinant adenoviruses were produced on PER.
Most important, the graph suggests that the recombinant adenoviruses are expressing the cd gene.
Recombinant adenoviruses have also been used to express angiogenic growth factors in-vivo.
Regimens containing the following recombinant adenoviruses were used to produce the anti-HIV responses.
Recombinant adenoviruses with increased stability are capable of incorporating larger genomes into virus particles ( virions ).
More particularly, the present invention relates to recombinant adenoviruses as vectors for gene therapy.
Immunogenicity of the recombinant adenoviruses for HIV was evaluated in chimpanzees under three treatment regimens.
Under these conditions, at least 75 % of neurons express the proteins encoded by recombinant adenoviruses.
Moreover, the recombinant adenoviruses may be of human or animal origin.
This example describes one method suitable for generating helper-independent recombinant adenoviruses expressing p53.
The response of the recombinant adenoviruses is monitored in 2 in vivo models.
Adenovirus packaging cells from monkey origin that are able to trans-complement E1-defective recombinant adenoviruses.
More particularly, the recombinant adenoviruses may be of human or animal origin.
This level of productivity is similar to that of other E1 and E4-defective recombinant adenoviruses.
These recombinant adenoviruses spread better and have an increased anti-tumour efficacy.
In a fourth, optional step, the recombinant adenoviruses are used for infecting,.
The recombinant adenoviruses of the present invention comprise structural and non-structural elements.
Based upon these considerations we generated two recombinant adenoviruses encoding two synthetic minigenes ( Fig 8 ).
Thus, the two recombinant adenoviruses are successively amplified in 12 well culture plates ampli.
Figure 12 is a schematic map of recombinant adenoviruses ACNTK, AANTK and AANCAT.
The recombinant adenoviruses were used to infect three HCC cell lines ( HLF, Hep3B and Hep-G2 ).
After 24 h, cells were infected with recombinant adenoviruses at a multiplicity of infection of 100.
The resulting recombinant adenoviruses are designated ACNTK, AANTK, and AANCAT respectively.
The system used to generate recombinant adenoviruses imposed a packing limit of 5kb for transgene inserts.
All recombinant adenoviruses were amplified in AD293 cells.
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Examples of using Recombinant
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With recombinant human erythropoietin and controls
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These recombinant types are expected to differ in stability
