Examples of 'region gene' in a sentence
Meaning of "region gene"
region gene - refers to a specific portion of a DNA sequence that contains genetic information. It is used in the context of genetics and molecular biology
How to use "region gene" in a sentence
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region gene
The mouse comprises an intact IgM constant region gene.
The constant region gene may be a mouse constant region gene.
Positive plaques were identified using the human kappa constant region gene as probe.
Human constant region gene sequences are available in the form of publicly accessible deposits.
It may sometimes be desirable to treat the variable region gene sequences with a mutating agent.
Engineered meganucleases with recognition sequences found in the human t cell receptor alpha constant region gene.
Orientation and sequence of the variable region gene was confirmed by restriction digestion and sequencing.
JH gene segments are operably linked to a constant region gene.
The mouse constant region gene is a Ck gene.
A V region gene can be isolated by a usual gene manipulation technique.
The construction required the combination of a human Cλ region gene module with a mouse Vλ region.
In this way the V region gene combination could be transferred as a unit between vectors.
TRC recognition sequences in the human TRC alpha constant region gene.
Preparation of C region gene segment modules by cDNA preparation and cloning.
Only two beta chain V region segments and two J region gene segments were found.
See also
The human k chain C region gene was cloned by the following procedure.
It contains the human IgG1 constant region gene.
Various V region gene families are interspersed within the V region cluster in humans.
In a preferred embodiment, the constant region gene encodes immunoglobulin µ.
In one embodiment, the artificial loci used comprise at least one artificial constant region gene.
In one embodiment, the constant region gene is a mouse constant region gene.
In another embodiment, the first and second meganucleases target constant region gene segments.
In the first step, variable region gene pools were amplified from approx.
In one embodiment, the promoter is a human immunoglobulin variable region gene segment promoter.
In one aspect, the constant region gene is a mouse constant region gene.
In one instance, the promoter is a human immunoglobulin variable region gene segment promoter.
The light-chain variable region gene was combined with a kappa 1 constant domain in a third construct.
In a specific embodiment, the immunoglobulin constant region gene is a mouse constant region gene.
Nucleotide sequence of the gene for the humanized anti-Tac light chain variable region gene.
In a specific case, the immunoglobulin constant region gene is a mouse constant region gene.
Nucleotide sequence of the gene for the humanized anti-Tac heavy chain variable region gene.
In one aspect, the immunoglobulin light chain constant region gene sequence is a mouse sequence.
In one embodiment, the vector further comprises at least one or more murine C region gene.
A variety of Fc region gene sequences e . g.
Such endogenous gene segments include diversity, joining and constant region gene segments.
The mouse comprises an IgM constant region gene that comprises a functional CH1 domain.
In a specific embodiment, the mouse comprises a humanized heavy chain variable region gene segment.
The isolation of a mouse immunoglobulin variable ( V ) region gene was carried out in the following manner.
It was likely that this fragment contained the 7E3 heavy chain variable region gene.
The method of claim 1, wherein the mouse constant region gene consists of a murine Fc region.
The IgY1 region gene is cloned from the vector pNY1.
Module vector - a plasmid DNA containing a constant or variable region gene module.
Preparation of C region gene segments by cDNA preparation and cloning ;.
This has been firstly revealed by isolating the variable region gene of JH2 antibody.
In one aspect, the constant region gene is a non-human constant region gene.
In one embodiment, the artificial loci used comprise at least one human C region gene segment.
It consists of four joining / constant region gene segments and two variable gene segments ( Figure 1 ).
By “ artificial Fc-region ” is meant an Fc-region encoded by an artificial constant region gene.
The mouse of claim 4, wherein the non-human constant region gene is a rodent constant region gene.
The 5 ' flanking region gene contains a " CAAT " consensus promoter sequence but no " TATA " sequence.
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