Examples of 'retroviral protease' in a sentence
Meaning of "retroviral protease"
retroviral protease: An enzyme responsible for cleaving proteins in retroviruses as part of their replication process. It is a target for antiretroviral drugs used to treat HIV and other retroviral infections
How to use "retroviral protease" in a sentence
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retroviral protease
Intermediates for the preparation of retroviral protease inhibiting compounds.
Retroviral protease inhibiting compounds.
The compounds disclosed therein are described as retroviral protease inhibitors.
Retroviral protease inhibitor combinations.
Novel inhibitors of retroviral protease.
Retroviral protease inhibitors.
Reagent and method for determining activity of retroviral protease.
An inhibitor of a retroviral protease will provide a therapeutic agent for diseases caused by the retrovirus.
Processes and intermediates for manufacturing retroviral protease inhibiting compounds.
Retroviral protease processes polyprotein precursors into viral structural proteins and replicative enzymes.
A recent alternate approach has been attempted to target the retroviral protease.
These compounds inhibit retroviral protease and thus inhibit the replication of the virus.
Method for making intermediates useful in synthesis of retroviral protease inhibitors.
An inhibitor of a retroviral protease should provide a therapeutic agent for diseases caused by the retrovirus.
Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors.
See also
Retroviral protease inhibitors also have been identified as a class of anti-retroviral agents.
Compounds ofthe present invention are useful as novel human retroviral protease inhibitors.
Therefore, retroviral protease inhibition provides an attractive target for antiviral therapy.
Also disclosed are processes and intermediates useful for the preparation of the retroviral protease inhibitors.
A retroviral protease inhibiting compound according to claim 1 having the formula wherein,.
The COMPOUND of the present invention is useful in inhibiting human retroviral protease.
Method of inhibiting a retroviral protease comprising administering an effective amount of a compound of Claim 1.
Background of the Invention This invention relates to novel inhibitors of retroviral protease.
Foldit - Crystal structure of a monomeric retroviral protease solved by protein folding game players.
Use of a composition of claim 75 for preparing a medicament for inhibiting a retroviral protease.
The method of Claim 5 in which the retroviral protease is HIV protease.
Use of a composition of Claim 49 for preparing a medicament for inibiting a retroviral protease.
Use of Claim 68 wherein the retroviral protease is HIV protease.
Use of a composition of Claim 25 for preparing medicament inhibiting a retroviral protease.
Intermediates for preparating non-peptide retroviral protease inhibitors.
Use of a compound of Claim 1 for preparing a medicament for inhibiting a retroviral protease.
Use according to claim 7 wherein the retroviral protease is HIV protease.
Use of a composition according to Claim 49 for preparing a medicament for inhibiting a retroviral protease.
Use according to Claim 20 wherein the retroviral protease is an HIV infection.
A is alkoxy, aralkoxy, aryloxy, cycloalkylalkoxy, for preparing a medicament for inhibiting a retroviral protease.
Use acccrding to Claim 55 wherein the retroviral protease is HIV protease.
Use of a compound of any of Claims 1-6 for preparing a medicament for inhibiting a retroviral protease.
Compound of claim 78 for use as an inhibitor of retroviral protease which is HIV protease.
European patent application no. 342541 discloses certain peptide compounds which are retroviral protease inhibitors.
The use recited in claim 1 wherein the retroviral protease is HIV protease.
Furthermore, as shown in Examples 16 and 17, such compounds are effective retroviral protease inhibitors.
Use of a composition of Claim 168 wherein the retroviral protease is HIV protease.
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Protease inhibitor drugs block this step
Dose of other protease inhibitors with low
Examples of using Retroviral
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Retroviral vectors are produced by genetically manipulating retroviruses
Targeted integration of a retroviral vector by homologous recombination
Proviral structure of three preferred retroviral vectors