Examples of 'ribonucleotide reductase' in a sentence
Meaning of "ribonucleotide reductase"
ribonucleotide reductase: An enzyme involved in the process of DNA synthesis
How to use "ribonucleotide reductase" in a sentence
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ribonucleotide reductase
Ribonucleotide reductase inhibitors and methods of use.
This conversion is catalysed by ribonucleotide reductase see figure.
Mutants of ribonucleotide reductase have been constructed by a number of methods.
The reduction of ribonucleotides to deoxyribonucleotides is catalyzed by ribonucleotide reductase.
Iron modulates ribonucleotide reductase activity.
Ribonucleotide reductase inhibitors such as hydroxyurea may also be used.
Large subunit of ribonucleotide reductase.
Hydroxyurea decreases the production of dNTPs by inhibiting the enzyme ribonucleotide reductase.
Ribonucleotide reductase serves other biological functions in addition to providing substrates for DNA replication.
Another enzyme involved with nucleotide metabolism is ribonucleotide reductase.
Ribonucleotide Reductase The enzyme ribonucleotide reductase reduces ribonucleoside diphosphates to the corresponding deoxyribonucleoside diphosphates.
Antisense oligonucleotides complementary to regions of the ribonucleotide reductase gene are particularly useful inhibitors.
Ribonucleotide reductase inhibition with reduction of cellular deoxynucleotide triphosphate ( dNTP ) pools.
The present invention relates to a novel process for the preparation of ribonucleotide reductase inhibitors.
Inhibitors of ribonucleotide reductase subunit 2 and uses thereof.
See also
Another target of gemcitabine is the enzyme ribonucleotide reductase RNR.
Furthermore, CdATP inhibits ribonucleotide reductase, the enzyme responsible for the conversion of ribonucleotides into deoxyribonucleotides.
Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase.
Hydroxyurea, a known ribonucleotide reductase inhibitor, is very different from ADA.
In a preferred embodiment of the invention, the mutation is in a ribonucleotide reductase gene.
The iron-containing proteins ribonucleotide reductase and aconitase are deactivated by NO.
In cells, azacitidine can be converted to decitabine by the enzyme ribonucleotide reductase.
Ribonucleotide reductase is a highly regulated, rate-limiting activity in the synthesis of DNA.
A homologous set of proteins is encoded by HSV-2 and exhibits a similar ribonucleotide reductase activity.
Ribonucleotide Reductase ( RNR ) is the sole enzyme that catalyzes the reduction of ribonucleotides into deoxyribonucleotides.
A mutation may be made in this region of the T4 ribonucleotide reductase using oligonucleotide-directed mutagenesis.
The disclosed oligonucleotides encompass antisense sequences complementary to the UTR of the ribonucleotide reductase R1 and R2.
Under these conditions the E. coli ribonucleotide reductase is inhibited and is not detected.
Furthermore, the dFdCDP acts as an inhibitor of the enzyme ribonucleotide reductase ( RR ).
Key words, ribonucleotide reductase turnover, proteolysis, ubiquitin, DNA replication.
The nucleic acid according to claim 9 wherein said mammalian ribonucleotide reductase R1 is a human ribonucleotide reductase R1.
A mammalian ribonucleotide reductase R1 ; or a biologically active analogue or derivative of the ribonucleotide reductase R1 of ( a ).
A biologically active analogue or derivative of the ribonucleotide reductase R1 of ( a ).
The small sub-unit of the ribonucleotide reductase of the turkey herpesvirus ( HVT ) has been sequenced.
A nucleic acid encoding a mammalian ribonucleotide reductase R1 ; or.
Ribonucleotide reductase ( RNR ) catalyzes the reaction that produces 2 ' - deoxyribonucleotides from their corresponding ribonucleoside 5 ' - diphosphates.
In addition, an exemplary class I ribonucleotide reductase ( nrdAB ) from Synechocystis sp.
Ribonucleotide reductase inhibitors, such as Hydroxyurea ( HU ) ;.
The method according to claim 48, wherein said mammalian ribonucleotide reductase R1 is a human ribonucleotide reductase R1.
The iron-dependent enzyme, ribonucleotide reductase ( RNR ), is essential for DNA synthesis.
The anti-apoptotic function of the R1 subunit of the ribonucleotide reductase of Herpes simplex viruses,.
A mammalian ribonucleotide reductase R1 ; or.
The use according to claim 32 wherein said mammalian ribonucleotide reductase R1 is a human ribonucleotide reductase R1.
The promoter regions of Y34.5 and ribonucleotide reductase ICP6 have been mapped.
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Examples of using Ribonucleotide
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Ribonucleotide reductase inhibitors and methods of use
A locked nucleic acid nucleotide is a modified ribonucleotide
The ribonucleotide reductases being inhibited are of cellular origin
Examples of using Reductase
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A reductase is an enzyme that catalyzes a reduction reaction
Reduced unspecific aldose reductase specific activity
Fumarate reductase complexes include four subunits
