Examples of 'rtks' in a sentence
Meaning of "rtks"
RTKS is not a known English word or acronym
How to use "rtks" in a sentence
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rtks
Mutations in RTKs are believed to be a driving force in cancer development.
Further agents include inhibitors of RTKs.
Two subfamilies of RTKs are specific to the vascular endothelium.
A recent review primarily focuses on the role or RTKs in tumor angiogenesis.
Other RTKs have been implicated in angiogenesis.
This sequence is the most divergent among all known RTKs.
Aberrantly regulated RTKs have been described in comparable human and canine cancers.
Ephs form the largest known subfamily of receptor tyrosine kinases RTKs.
The RTKs comprise a large family of transmembrane receptors with diverse biological activities.
Sunitinib inhibits cellular signaling by targeting multiple receptor tyrosine kinases RTKs.
Eph RTKs and their ephrin ligands play important roles in embryonic vascular development.
Several intracellular substrate proteins that associate with RTKs have been identified.
RTKs overactivation induces cell transformation and tumorigenesis notably by promoting survival.
There is a strong preference for certain domains to occur in the ectodomain of RTKs.
Growth factor ligands and their respective RTKs are required for tumor angiogenesis and growth.
See also
Cell proliferation of cancer cells is dependent on the activity of these aberrant RTKs.
RTKs are important in the transmission of biochemical signals across the plasma membrane of cells.
These same PTPases have also been shown to modulate the activity of certain RTKs.
The association between RTKs or its downstream pathways with DNA repair mechanisms is unclear.
A novel technology capable of specifically detecting phosphorylation events in ErbB family RTKs has been developed.
Finally, both RTKs and CTKs are currently suspected as being involved in hyperimmune disorders.
The compounds of the present invention are efficient inhibitors of TAM family RTKs.
Because of their configuration, RTKs can be envisioned as membrane-associated allosteric enzymes.
Polypeptide ligands known as growth factors or cytokines, are known to activate RTKs.
Tyrosine phosphorylation of certain RTKs is observed by the identification of high to low-intensity signals.
Cysteine-rich domains of variable length are also commonly found in RTKs.
The association between abnormalities in RTKs and disease are not restricted to cancer, however.
The fibroblast growth factor receptor kinases ( FGFRs ) represent another type of RTKs.
In addition, a group of RTKs with seven lgLs has been proposed to represent a separate subfamily.
Eph receptors in turn compose the largest known subfamily of receptor protein-tyrosine kinases RTKs.
Finally, both RTKs and non-receptor type kinases have been connected to hyperimmune disorders.
The compound of claim 8 as efficient inhibitors of TAM family RTKs.
RTKs ( also known as growth factor receptors ) play an important role in many cellular processes.
AXL can be activated by its ligand GAS6 or by a crosstalk with other RTKs.
RTKs are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones.
This result was further confirmed by a genetic interaction between Rab11 and RTKs.
C-Met, is the prototypic member of a sub-family of RTKs which also includes RON and SEA.
Comparison of the Flk-1 amino acid sequence with related RTKs.
VEGF is known to specifically bind to RTKs including VEGFR-1 and VEGFR-2.
According to its deduced amino acid sequence, Flt4 belongs to class III RTKs.
For example, suitable activation state-dependent antibodies specific for dimerized RTKs include antibodies to HER1 Cat.
Besides EGFR and PDGFR-a, the receptor UFO / AXL was one of the most prominently expressed RTKs.
At present, at least nineteen ( 19 ) distinct subfamilies of RTKs have been identified.
