Examples of 'rufinamide' in a sentence
Meaning of "rufinamide"
Rufinamide is a term used in medicine to describe a medication with anti-epileptic properties, commonly used to treat seizures
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- A triazole derivative used as an anticonvulsant
How to use "rufinamide" in a sentence
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rufinamide
Rufinamide is active in a range of animal models of epilepsy.
Inovelon contains the active substance rufinamide.
No data on the interaction of rufinamide with alcohol are available.
Rufinamide was evenly distributed between erythrocytes and plasma.
The mechanism of action of rufinamide is still unknown.
Rufinamide was not genotoxic and had no carcinogenic potential.
Improved process for preparing rufinamide intermediate.
Is not known if rufinamide is excreted in human breast milk.
Inovelon is a medicine containing the active substance rufinamide.
The bioavailability of rufinamide is dependent on dose.
Rufinamide is almost exclusively eliminated by metabolism.
There is no specific antidote for rufinamide.
Potential for rufinamide to affect other medicinal products.
Inovelon contains a medicine called rufinamide.
Higher rufinamide doses may result in a more pronounced induction.
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The active substance is rufinamide.
Rufinamide should be withdrawn gradually to reduce the possibility of seizures on withdrawal.
There is limited information on the use of rufinamide in older people.
Rufinamide is an anticonvulsant medication.
There is limited information on the use of rufinamide inolder people.
The toxicity profile of rufinamide in juvenile animals was similar to that in adult animals.
Risk related to rufinamide.
Rufinamide was not teratogenic in mice, rats or rabbits.
No data are available on the effects on fertility following treatment with rufinamide.
All patients who develop a rash while taking rufinamide must be closely monitored.
Women of childbearing potential must use contraceptive measures during treatment with rufinamide.
Withdrawal of rufinamide.
When rufinamide treatment is to be discontinued, it should be withdrawn gradually.
Side effects of rufinamide.
If this reaction is suspected, rufinamide should be discontinued and alternative treatment started.
Discontinuation of rufinamide.
Rufinamide modulates the activity of sodium channels, prolonging their inactive state.
Serious antiepileptic drug hypersensitivity syndrome has occurred in association with rufinamide therapy.
By attaching to these channels, rufinamide prevents them from becoming activated.
Each millilitre contains 40 mg of rufinamide.
No significant changes in rufinamide concentration are observed following co-administration with lamotrigine, topiramate or benzodiazepines.
Prednisone ( to treat inflammatory disease ) rufinamide to treat seizures.
In a thorough QT study, rufinamide produced a decrease in QTc interval proportional to concentration.
Rufinamide ( to treat seizures ).
These events led to rufinamide discontinuation in 20 % of the cases.
Mechanism of action Rufinamide modulates the activity of sodium channels, prolonging their inactive state.
Inovelon contains the active substance rufinamide and has been authorised since January 2007.
Olson HE, et al . Rufinamide for the treatment of epileptic spasms.
