Examples of 'sacubitril' in a sentence
Meaning of "sacubitril"
sacubitril (noun) - a drug used in the treatment of heart failure, often in combination with valsartan, to reduce the risk of cardiovascular death and hospitalization for heart failure
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- An antihypertensive drug used in combination with valsartan to treat heart failure.
How to use "sacubitril" in a sentence
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sacubitril
The active substances are sacubitril and valsartan.
Sacubitril blocks the breakdown of natriuretic peptides produced in the body.
There are no data from the use of sacubitril in pregnant women.
Therefore, the burden of proof is on the clinical benefit of sacubitril.
It consists of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan.
Entresto is a heart medicine that contains the active substances sacubitril and valsartan.
Sacubitril is the new drug, which acts by inhibiting neprilysin action.
Neparvis is a heart medicine that contains the active substances sacubitril and valsartan.
One would therefore randomize patients to sacubitril vs. placebo, without interfering with the adjunctive treatment.
The average apparent volume of distribution of valsartan and sacubitril were 75 litres to.
The calcium salt of sacubitril was prepared according to the procedure presented in Example 2.
Described herein are solid forms of the calcium salt of sacubitril in variable molar ratios.
The cyclohexyl ammonium salt of sacubitril was prepared according to the procedure presented in Example 1.
It dissociates into two active substances, sacubitril and valsartan.
Entresto sacubitril / valsartan.
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No evidence of embryo-foetal toxicity or teratogenicity was observed in rats treated with sacubitril.
Current literature continues to suggest that sacubitril may be a promising therapy for heart failure.
LCZ696 is a combination molecule made up of valsartan chemically combined with sacubitril.
These solid forms are suitable for preparation of sacubitril with a high chemical and optical purity.
Neprilysin inhibitors, Entresto is a combination of valsartan, an ARB inhibitor and a new agent, sacubitril.
The two active substances in Neparvis, sacubitril and valsartan, work in different ways.
In fact, it is a mixture of 320 mg of traditional valsartan with sacubitril.
The two active substances in Entresto, sacubitril and valsartan, work in different ways.
Sacubitril / valsartan is co-crystallized sacubitril and valsartan, in a one-to-one molar ratio.
Pre - and postnatal development studies in rats conducted with sacubitril at high doses up to.
Fig . 8, XRPD pattern of sacubitril calcium salt crystalline Form I.
LCZ696 is a combination neprilysin inhibitor sacubitril and valsartan.
Sacubitril is further metabolised to the active metabolite LBQ657.
If your child has taken a drug that has sacubitril in it in the last 36 hours.
Sacubitril is a prodrug that is activated to sacubitrilat ( LBQ657 ) by de-ethylation via esterases.
The average apparent volume of distribution of valsartan and sacubitril were 75 litres to 103 litres, respectively.
Sacubitril ( / səˈkjuːbɪtrɪl / ; INN ) is an antihypertensive drug used in combination with valsartan.
In vitro data indicate that sacubitril inhibits OATP1B1 and OATP1B3 transporters.
Fig . 10, XRPD pattern of sacubitril calcium salt semicrystalline Form III.
