Examples of 'semaphorin' in a sentence
Meaning of "semaphorin"
semaphorin (noun): A semaphorin is a type of signaling protein that is involved in guiding the growth of nerve cells. It plays a crucial role in the development of the nervous system. This term is primarily used in the field of neurobiology and biochemistry
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- Any of a class of proteins that assist growing axons to find an appropriate target and to form synapses
How to use "semaphorin" in a sentence
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semaphorin
Wherein said agent specifically binds semaphorin polypeptide.
Regulation of semaphorin guidance activity in the developing nervous system.
Methods of determining an expression of a semaphorin receptor are known in the art.
Another semaphorin gene has been identified in several strains of poxvirus.
Preferred nucleic acid portions encode a unique semaphorin peptide.
Use of a compound having a semaphorin inhibitory activity which is obtained by culturing Penicillium sp.
Antibody or probe capable of specifically interacting with a semaphorin subtype.
Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.
These results reveal that the compounds of the present invention strongly inhibit semaphorin.
An isolated antibody that specifically binds a semaphorin polypeptide portion according to claim 1 or 2.
To modulate semaphorin translation, cells may be transfected with complementary antisense polynucleotides.
Scientists thus hypothesize that there is considerable redundancy of Semaphorin family types.
Typically, the subject for whom the semaphorin is selected is a mammalian subject e . g.
Semaphorin 3c variants, compositions comprising said variants and methods of use thereof.
These inhibitors belong to the so-called semaphorin family.
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However, most functions of many semaphorin families have not yet been discovered in detail.
Preferably, the antibody specifically binds at least one epitope of the semaphorin receptor.
Typically, the invention 's semaphorin peptide encoding polynucleotides are associated with heterologous sequences.
According to some embodiments of the invention, the semaphorin is a class 3 semaphorin.
However, more recently semaphorin overexpression has been correlated with tumor invasión and metastasis.
In a different embodiment, the anti-Nrp antibody inhibits semaphorin biological activity in vitro.
The 4D Semaphorin is also related to the formation of blood vessels.
In an additional embodiment, the anti-Nrp antibody inhibits semaphorin biological activity in vivo.
Nrp1 and semaphorin antibodies.
The kit may also comprise other agents useful for analyzing semaphorin receptor expression e . g.
SEMA4A is a member of the semaphorin family of soluble and transmembrane proteins.
He 's also working on an antibody that will screen specifically for semaphorin 3A.
However, most functions of many semaphorin families have not yet been clarified in detail.
Action of xanthone compound to suppress neurite elongation inhibitory activity of semaphorin 3A.
Exemplary semaphorin receptors include, neuropilins, plexins and integrins.
The invention also provides vectors comprising nucleic acids encoding semaphorin peptides, polypeptides or analogs.
Semaphorin 7a plays a critical role.
SEMA3F is a secreted member of the semaphorin III family.
Thus, for example if a semaphorin has a high affinity for a receptor e . g.
According to some embodiments of the invention, the semaphorin is sema3E.
According to one embodiment, the semaphorin belongs to the class-3 semaphorin sub-family.
Such semaphorin molecules can be, e.g., multimerized and / or immobilized on a surface or a bead.
Here, we examined the contribution of Semaphorin 3 ( SEMA3 ) signaling to the development of these circuits.
In particular, NP-1 is known to mediate the growth cone-collapsing and chemorepulsive activity of semaphorin 3.
The human semaphorin is found in placenta, testis, ovary, spleen, dendritic cells, and B cells.
The peptide of claim 1, wherein the peptide is derived from human semaphorin 3A ( Sema3A ) protein.
Semaphorin 3A and 3F, key players in myelin repair in multiple sclerosis?
The semaphorin 3D polypeptides may comprise the full length sequence of SEQ ID NO, 29.
