Examples of 'significant drawback' in a sentence

Meaning of "significant drawback"

A significant drawback refers to a major disadvantage or limitation of something. It indicates a substantial negative aspect that can significantly impact the overall effectiveness or quality of a person, object, or situation.

How to use "significant drawback" in a sentence

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Advanced
significant drawback
The invention aims to overcome this significant drawback.
A significant drawback of inactivated vaccines is the threat of residual infectivity.
This latter solution has however a significant drawback.
A significant drawback to biomimetic chemical agents is their modest service life.
But these known methods have a significant drawback.
This is a significant drawback to using nanopillars as a part of the manufacturing process.
The need to use high concentrations is a significant drawback.
The only significant drawback of the game is a large amount of advertising.
The presence of zinc and chloride impurities is a significant drawback.
This is a significant drawback since the mazes tend to be relatively predictable.
From a safety and a regulatory perspective this is a significant drawback.
The second significant drawback is the limitation of a system of this type.
This last solution also presents a significant drawback in terms of safety.
The only significant drawback is the slow compilation on big projects.
This known printing cylinder support unit has a significant drawback.

See also

This significant drawback is avoided by the teachings of the present invention.
Deforestation of woods and rain forests is a significant drawback with wooden pencils.
The most significant drawback is the negative impact on your credit report.
Prior motor operated window shade apparatus have had a significant drawback of noisy operation.
This may be a significant drawback depending on the active substance under consideration.
The soft keyboard still needs improvement and the high temperatures during load are a significant drawback.
A significant drawback to such devices includes the use of the discrete elements.
The elusiveness of EE benefits is a significant drawback to potential investors.
A significant drawback of the method is that it requires enormous amounts of immobilized antibody.
Administrative time required by TTO Directors to manage group grants can also be a significant drawback.
Another significant drawback of this option is the need of taking measurements outdoors.
The second option… also has a significant drawback.
The only significant drawback of using minoxidil is that it must be applied for life.
However, the space it requires constitutes a significant drawback.
Another significant drawback of love unions is your high degree of expectations and presumptions.
For certain applications, this constitutes a significant drawback.
A significant drawback to the synthetic oligonucleotide approach is that it would require periodic administrations.
However, this adjustment system presents a significant drawback.
The most significant drawback of enteric coating is the variability in gastric emptying time.
However, products containing marine oil have a significant drawback.
This is a significant drawback for assembling the timepiece and adjusting the balance shake.
Despite the aforementioned advantages, a significant drawback to ammonia recovery processes exists.
The most significant drawback of using caffeine for weight loss is the side effects.
However, the need to use organic solvents is a significant drawback of this method.
One significant drawback to many joint replacements is the extended and painful patient recovery.
Nevertheless, pre-filled syringes also have a significant drawback in the marketplace.
The most significant drawback is the striations that are caused by uneven curing and stress.
However, these techniques exhibit varied success and have a significant drawback.
A significant drawback is presented by the difficulty associated with assembling such back support systems.
However, air transport has a single significant drawback - the considerable cost of a ticket.
A significant drawback is that all VM management operations are serialized.
Taxol 's strength against cancers of diverse tissue origin also represents a significant drawback.
The most significant drawback of this method is the power loss associated with this method.
However, as stated above, this method had the significant drawback of a limited spatial resolution.
There is a significant drawback of calculating the Payback Period using such a simple set of assumptions.

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Just take a drawback from our salaries
A lack of pubic hair is not necessarily a drawback
Dust may be one drawback of this bedding
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Examples of using Significant
Significant resources had been allocated for education
You have done significant damage to your heart
Significant direct and indirect employment created
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