Examples of 'silyl protecting' in a sentence
Meaning of "silyl protecting"
silyl protecting: Not a common phrase in English. Could be a typo or misspelling
How to use "silyl protecting" in a sentence
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silyl protecting
Removing the silyl protecting groups.
Silyl protecting groups may be removed by simple hydrolysis or alcoholysis.
An example of this is the use of a silyl protecting group on a alcohol.
A silyl protecting group at an amino function greatly increases its reactivity.
In a working example an acyl group replaces the silyl protecting group.
The silyl protecting group was cleaved in the course of the reaction sequence.
In a preferred embodiment of the invention the silyl protecting group is preferably trimethylsilyl.
Most silyl protecting groups are easily cleaved by contact with water or an alcohol.
Halosilanes are generally employed to introduce silyl protecting groups into organic compounds.
The silyl protecting groups are removed using hydrofluoric acid to produce simvastatin butylamide XIV.
Oxygen atoms are preferably enolized with the silyl protecting groups noted above.
The silyl protecting group is removed with fluoride to arrive at compound 7.
It is most convenient to enolize the oxygens by providing silyl protecting groups for them.
Among the conventional silyl protecting groups are trimethylsilyl and dimethyl - t - butylsilyl.
A reactive group may be protected, preferably by silyl protecting group technology.
See also
The two silyl protecting groups of 9 are removed and replaced by benzoyl protecting groups.
The same may be said of the silyl protecting group represented by Y.
In another specific embodiment, the alcohol protecting group is a silyl protecting group.
Even more specifically still, the silyl protecting group is tert-butyldimethylsilyl.
A suitable desilylating agent is a compound, which removes the silyl protecting group.
The silyl protecting group is then removed, for example, using tetrabutyl ammonium fluoride.
Is a conventional silyl protecting group ;.
For example, one equivalent of hexamethyldisilazane provides two equivalents of a silyl protecting group.
In another even more specific embodiment, the silyl protecting group is tert-butyldimethylsilyl.
In oligonucleotide synthesis, the monomer is preferably a phosphoramidite nucleoside having a 5 ' silyl protecting group.
Ester, alkyl, aryl and silyl protecting groups may be used to block hydroxyl groups.
In one embodiment of the invention, the hydroxyl protecting group is a silyl protecting group.
Silyl protecting groups are advantageously split off with fluorides, for example, tetraethylammonium fluoride.
The method according to claim 1, wherein said silyl protecting reagent is a silyl halide.
The usual silyl protecting groups as discussed above are used for this purpose, also.
Treatment with hydrogen fluoride / pyridine removes any silyl protecting groups that may be present.
A preferred silyl protecting group is dimethyl-t-butylsilyl.
A compound according to claim 1 having the formula wherein R2 is a silyl protecting group.
Removal of the silyl protecting group with a base, e . g.
The compound of formula the compund of formula wherein R2 is a silyl protecting group ;.
More preferably, the silyl protecting group is tert-butyldimethylsilyl.
In certain embodiments, Raa is an acyl protecting group, and Rbb is a silyl protecting group.
This was stirred until the silyl protecting group was removed ( 2 h ).
Step P38 includes preparation of a first chain including at least one monomer having a silyl protecting group.
Preferably, the silyl protecting group is triethylsilyl, triisopropylsilyl, or tert-butyldimethylsilyl.
Step P40 includes deprotecting the first chain by removing the silyl protecting group.
Is silyl protecting group selected from tert-butyldimethylsilane, tert-butyldiphenylsilane or triisopropylsilane ;.
Is tetrahydrofuranyl, tetrahydropyranyl or a silyl protecting group ;.
Even more specifically, the silyl protecting group is triethylsilyl, triisopropylsilyl, or tert-butyldimethylsilyl.
Is an acyl protecting group, a coupling group, or a silyl protecting group ;.
To protect the triple bonds, the silyl protecting group at carbon 17 is replaced by acetate.
Eventually, this problem was overcome by using a combination of allyl, isopropylidene, and silyl protecting groups.
Conveniently the silyl protecting group is removed during the work-up procedure of step ( ii ).
The example of compound 1 actually described utilizes this silyl protecting group at the 2 ' position.
Preferred silyl protecting groups include dimethyl-t-butylsilyl, trimethylsilyl, phenyldimethylsilyl, benzyldimethylsilyl and the like.
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The silyl compound hydrolysed very quickly
One type may be a silyl ester copolymer
Silyl ethers and chlorides are moisture curing
Examples of using Protecting
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Whatever they are protecting does not belong to them
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