Examples of 'single chain antibody' in a sentence
Meaning of "single chain antibody"
single chain antibody - A single chain antibody is a type of antibody derived from only one chain of the usual antibody structure, often used in research or medical applications
How to use "single chain antibody" in a sentence
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single chain antibody
The antibody may be a single chain antibody.
The single chain antibody optionally is a camelid antibody.
The antibody molecule can be a single chain antibody.
Such a single chain antibody is preferably a recombinant scFv antibody.
For display and selection of single chain antibody fragments.
The single chain antibody constructs were made by the following procedure.
The antibody is preferably a monoclonal antibody or single chain antibody.
A single chain antibody format is chosen for convenience in subsequent expression and screening steps.
The intracellular binding protein can be a single chain antibody.
A single chain antibody contains a light and a heavy variable region joined together by a linker.
An antibody fragment may optionally comprise a single chain antibody fragment.
Single chain antibody constructs used to generate ARM complexes.
The antibody fragment may optionally be a single chain antibody fragment.
The bispecific single chain antibody could be specifically detected by Western Blot.
The antibody fragment may comprise a single chain antibody fragment.
See also
A single chain antibody of claim 7 for use in medicine.
Another recombinant epitope binding protein is the single chain antibody.
In some examples, the single chain antibody further contains a peptide linker.
An antibody of the invention may be an antibody fragment or a single chain antibody.
In a preferred approach, the single chain antibody was prepared using a phage display library.
This molecular weight corresponds to the bispecific single chain antibody.
Such kits wherein said single chain antibody is derived from a phage display library ;.
The term scFv is used interchangeably to refer to a single chain antibody.
Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen.
These can be used as targets for scanning single chain antibody libraries.
The DNA of the single chain antibody inserts of ELISA-positive transformants are sequenced.
The methods also include embodiments where the antibody is a single chain antibody.
Preferably, the antibody is a single chain antibody where a VH domain is linked to a VL domain.
The selected cell culture system preferably secretes the single chain antibody product.
The single chain antibody can be mono - or bi-specific, and can be bivalent or tetravalent.
The first links the heavy and light domains of the single chain antibody.
The purified single chain antibody can be measured by the method described in the above 1 ( 5 ).
Here the term Sab is not limited to just a human or a humanised single chain antibody.
An advantageous variant of this bispecific single chain antibody is from N terminus to C terminus,.
A further preferred embodiment concers the DNA sequence coding for the single chain antibody.
This invention further provides an isolated single chain antibody of 8H9 or a derivative thereof.
Maximal cytokine release was observed after administration of 10 µg of bispecific single chain antibody.
Preferably, the antibody is a single chain antibody or ScFv.
Maximal cytokine release was observed after administration of 10 microgram of bispecific single chain antibody.
Dimers of a single chain antibody ( scFV2 ), are also contemplated.
One example of a trivalent single chain antibody is,.
A dimer of a single chain antibody ( scFV2 ), defined as a dimer of a scFV.
In one embodiment, the antibody is a single chain antibody.
The single chain antibody of claim 29 or 30, wherein the single chain antibody is an scFv.
In certain embodiments, the antibody is a single chain antibody.
Formats of bispecific single chain antibody molecules comprising anti-CEA and anti-CD3 specificities ( Table 1 ).
In another preferred embodiment, said antibody is a single chain antibody.
Fv, Fab and Fab ′ fragments and single chain antibody fragments, e . g.
More preferably, said antibody is a human antibody, a chimeric antibody or a single chain antibody.
In some embodiments, the ligand is a monoclonal antibody, a single chain antibody or a single domain antibody.
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