Examples of 'small-molecule' in a sentence

Meaning of "small-molecule"

small-molecule (noun) - A small-molecule refers to a low molecular weight compound, typically having a size of less than 900 Daltons. Small molecules are often used in scientific research and drug development due to their ability to interact with specific biological targets

How to use "small-molecule" in a sentence

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small-molecule
The compound is a small-molecule therapeutic.
Small-molecule cocktails can convert fibroblasts into functional neurons.
Such inhibitors may be peptides or small-molecule compositions.
The mediators are small-molecule compounds that are oxidized by laccases.
Proteins can bind to other proteins as well as to small-molecule substrates.
However, manufacturers of small-molecule generics will experience accelerating growth.
It is therefore an object of the invention to provide small-molecule neurotrophic agents.
Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia.
An organic drug may be any small-molecule therapeutic material.
Thus, biosimilars require a different regulatory framework compared to small-molecule generics.
Identifying the proteins to which small-molecule probes and drugs bind in cells.
Most often, targeted therapies are either monoclonal antibodies or small-molecule drugs.
Both soft and hard corals are rich in small-molecule natural products, in particular terpenoids.
These drugs are also called signal-transduction inhibitors or small-molecule drugs.
Funding to develop your small-molecule lead into a drug candidate for animal health.

See also

The institute has started screening such small-molecule compounds.
One such target for small-molecule modulation of antiangiogenic and antiproliferative activity is c-Met.
Tyrosine kinase inhibitors and proteasome inhibitors are examples of small-molecule drugs.
A fusión partner may be a small-molecule mimetic of a protein that targets a therapeutically useful target.
Existing treatment of fungal allergy is through use of steroids or small-molecule anti-fungal agents.
There is still a desire to discover small-molecule compounds that are especially potent antipicornaviral agents.
Additionally, the description is useful for the production of small-molecule drug candidates.
Complex small-molecule generics and hybrids form the backbone of our product portfolio.
To block this neurotoxicity, we designed and synthesized small-molecule inhibitors targeting gingipains.
Most small-molecule drugs are bitter-tasting and therefore require some degree of taste masking.
There is still a desire, however, to discover small-molecule compounds that are especially potent antipicomaviral agents.
They induced a pluripotent state in adult cells from mice using seven small-molecule compounds.
Our work aims at the development of small-molecule drugs targeting specific oncogenic miRNAs production.
Materials for the delivery of a compound include a wide range of polymers and small-molecule matrices.
Small-molecule kinase inhibitors have therefore emerged as a new class of efficient treatments against these diseases.
Thus, a need exists for selective and potent small-molecule protein tyrosine kinase inhibitors.
Thus, biosimilars require a different regulatory framework compared to xanax prescription writing small-molecule generics.
They combine some of the best features of small-molecule and biologic drugs into one.
A number of small-molecule DMARDs are used today in RA therapy.
Antibodies are the basis of many modern drugs and differ from the older, small-molecule drugs.
The differentiating fat cells secreted a small-molecule peptide called cathelicidin, specifically in response to the infection.
The original definition of the term " riboswitch " specified that they directly sense small-molecule metabolite concentrations.
Acetylcholine is a typical small-molecule transmitter that obeys the principles of synthesis and release stated earlier.
These studies also display the challenge in the development of small-molecule agonists for peptide-bound GPCRs.
Initial tests with other small-molecule compounds did not have a positive effect on the reprogramming efficiency.
VEGFRs antagonists could be humanized monoclonal antibodies or small-molecule inhibitors.
They then identified a small-molecule inhibitor that mimicked the interaction of the phage with its host.
Nanostructures made of DNA strands can encapsulate, release small-molecule drugs.
Rislenemdaz is a small-molecule antagonist of the NMDA receptor.
In other embodiments, the patient is not receiving a small-molecule DM therapeutic agent.
A small-molecule OLED that is deposited on a substrate can be used.
Some of these strategies include the use of HGF antagonists and small-molecule inhibitors.
To date, a number of small-molecule CDK inhibitors are currently under clinical trials.
GnRH antagonists include peptides such as cetrorelix and non-peptide and small-molecule compounds such as elagolix.
Ibrutinib is a small-molecule inhibitor of BTK.

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