Examples of 'solid amorphous' in a sentence
Meaning of "solid amorphous"
solid amorphous ~ describing something that is both fixed or stable yet shapeless or undefined
How to use "solid amorphous" in a sentence
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solid amorphous
A pharmaceutical composition comprising a solid amorphous dispersion of.
The solid amorphous dispersion was in the form of small particles.
The carbon foam can comprise solid amorphous carbon strands.
A solid amorphous dispersion of the drug may be fed into an extruder.
It is sometimes desired to form a solid amorphous dispersion of a drug and a polymer.
The solid amorphous dispersion is usually in the form of small particles.
Certain compounds of the invention exist as solid amorphous or crystalline forms.
The solid amorphous compositions of the invention have interesting optical and electrical properties.
By amorphous body is meant a preferably solid amorphous body which is not crystallized.
The initial solid amorphous dispersion may also be treated by exposure to a mobility enhancing agent.
The polymer may be neutralized prior to formation of the solid amorphous dispersion.
The solid amorphous dispersion of drug is prepared by spray-drying.
Additives may be incorporated into the solid amorphous dispersion during or after its formation.
This solid amorphous dispersion is a solid, which is further contained within a dosage form.
In contrast to anisotropic crystals, solid amorphous substances are isotropic.
See also
Inhalable solid amorphous particles comprising tiotropium bromide and a co-solid.
Preferably, at least a major portion of apixaban in the solid amorphous dispersion is amorphous.
In addition, the solid amorphous dispersion should be substantially homogeneous.
The coating is sprayed into this rope, coating the solid amorphous dispersion.
Preferably, apixaban in the solid amorphous dispersion is substantially amorphous.
Preferably, removal of the solvent results in the formation of a substantially homogeneous, solid amorphous dispersion.
The spray-dried solid amorphous dispersion formed by this process was collected in a cyclone.
According to the present invention, the solubility-improved form is a solid amorphous dispersion of apixaban.
In one method, a solid amorphous dispersion of the drug and polymer is initially formed.
It comprises solid crystalline material, usually also with presence of some solid amorphous material.
The process according to claim 1 wherein said solid amorphous paroxetine is free of calcium polycarbophyl.
The solid amorphous dispersion within the granules are substantially separate from the HMG-CoA reductase inhibitor.
The dosage form of claim 8 wherein said solid amorphous dispersion is a spray-dried dispersion.
For example, Compound 1 is present as an amorphous compound as a component of a solid amorphous dispersion.
The spray-dried solid amorphous dispersion was then formed using the following procedure.
Preferably, at least a major portion of the CETPI in the solid amorphous dispersion is amorphous.
The solubility-improved form is a solid amorphous dispersion comprising apixaban and a concentration-enhancing polymer.
In one aspect, the CETP inhibitor composition has a high loading of the solid amorphous dispersion.
The present invention further provides solid amorphous particles obtainable by the above-described process.
Hydrolysis of the solubilized partial hydrozylate leads to the formation of a solid amorphous SiO â‚‚ - TiO â‚‚ cogel.
The coating substantially separates the solid amorphous dispersion from the HMG-CoA reductase inhibitor.
The solid amorphous dispersion, generally includes Compound 1 and a polymer.
In another method, the coating is applied to the solid amorphous dispersion using a wet-granulation technique.
The solid amorphous dispersion, generally includes Compound 1 and Compound 2 and a polymer.
Preferably, the CETP inhibitor in the solid amorphous dispersion is substantially amorphous.
In addition to the solid amorphous dispersion, the CETP inhibitor composition may also comprise a disintegrant.
Control 2A consisted of the untreated initial solid amorphous dispersion used to form Example 2.
Thus, the base and solid amorphous dispersion may be blended together using wet - or dry-granulation.
The source of silicon can be, for example, a silica soil, solid amorphous silica, or a silicate.
Apixaban was in the form of a solid amorphous dispersion, made as described in Example 1.
The coated HMG-CoA reductase inhibitor is then mixed with the solid amorphous dispersion 52.
In this test, 4.5 mg of the spray-dried solid amorphous dispersion was placed into a microcentrifuge tube.
In the past, the art has employed as viscosity index improvers, solid amorphous ethylene-propylene polymers.
As discussed below, such high Tgs result in solid amorphous dispersions with excellent physical stability.
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