Examples of 'somatic mutation' in a sentence
Meaning of "somatic mutation"
Somatic mutation: This phrase refers to a genetic alteration or change that occurs in the cells of an organism's body, excluding the germ cells. Somatic mutations can lead to various outcomes, including cancer and genetic diseases
How to use "somatic mutation" in a sentence
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somatic mutation
I did not identify a new recurrent somatic mutation.
The somatic mutation theory of ageing.
This mutation is therefore assumed to be a somatic mutation.
A nucleotide variation may be a somatic mutation or a germline polymorphism.
Somatic mutation theory of aging is one.
These differences are probable sites of somatic mutation.
Any somatic mutation may be informative.
You have a cryogenic malignancy and a somatic mutation.
Such diversity relies on somatic mutation for the generation of antibody diversity.
This is presumably due to somatic mutation.
Somatic mutation arose in somatic cells at different levels of postzygotic evolution of an individual.
This result indicates a somatic mutation.
Our understanding of somatic mutation rates in normal human cells is still relatively rudimentary.
A quantitative measurement for the human somatic mutation rate.
Each of junctional diversity and somatic mutation events are discussed in additional detail below.
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In some of these analyses the nucleotide variation is a somatic mutation.
The nucleotide variant may be somatic mutation or pattern polymorphism.
They are typically detected by variegation arising from somatic mutation.
A germline mutation is in contrast to a somatic mutation which is acquired in a single body cell.
Antibodies are further known to increase their diversity by somatic mutation.
The researchers also analyzed the somatic mutation frequencies of all human genes.
One source of light chain diversity can be from somatic mutation.
Human melanomas exhibit relatively high somatic mutation burden compared to other malignancies.
A difference in the sequence in the two tissues indicates a somatic mutation.
It is a somatic mutation of the PIGA gene.
It will remain to be determined if the in vivo somatic mutation was optimal.
Germline replications and somatic mutation accumulation are independent of vegetative life span in Arabidopsis.
The sample is identified as colorectal cancer if the somatic mutation is determined.
Somatic mutation A mutation that occurs in a somatic cell.
We serendipitously discovered one additional somatic mutation in a colorectal cancer.
Human antibodies achieve high affinity and specificity by the progressive process of somatic mutation.
A tumor antigen is generated by the somatic mutation of a wild type gene.
From this point of view is the formation of the tumor caused by somatic mutation.
Alternatively, four-leaf clovers could be caused by somatic mutation or a developmental error of environmental causes.
This indicates that the altered RNase protection pattern was the result of a somatic mutation.
Thus somatic mutation allows affinity maturation - the production and selection of high affinity antibodies.
Any method known in the art for determining a somatic mutation can be used.
However, cells with a somatic mutation that stimulates cell division can increase in number and spread.
The monoclonal nature of endometriomas suggests that they arise from a somatic mutation in a precursor cell.
Like all the aging theories, the somatic mutation theory only explains a piece of the puzzle.
Antigen responsivity leads to immunoglobulin heavy chain isotype switching and variable region somatic mutation.
An increase, decrease or stable level of said somatic mutation over time is identified.
Increased diversity is also provided by recombination with the various D and J regions and somatic mutation.
Furthermore, somatic mutation of single bases also contributes to Ig diversity.
The TCR and Ig genes can generate millions of distinct proteins vía somatic mutation.
Somatic mutation in TP53 gene is associated with bladder cancer development and progression.
However, there are proven cases of somatic mutation.
Somatic mutation expands the range of antibody affinities encoded by clonal progeny of a B-cell.
Consequently, it must have arisen through somatic mutation.
A splice somatic mutation in p63 was detected in all affected individuals, but not in their parents.
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Examples of using Mutation
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Such a peculiar mutation has never been on record
It looks like some kind of pigment mutation
Whether a mutation is naturally or artificially induced is irrelevant
Examples of using Somatic
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Could be somatic dysfunction at the myofascial junction
Plate count and somatic cell count
Psychosomatic diseases become somatic ones if ignored
