Examples of 'specific cleavage' in a sentence
Meaning of "specific cleavage"
specific cleavage ~ in biology, specific cleavage refers to the precise and coordinated way in which an embryo's cells divide and differentiate to develop into specialized tissues and organs
How to use "specific cleavage" in a sentence
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specific cleavage
Ribozymes may cleave mRNA at specific cleavage sites.
Specific cleavage at any site within such a structure is contemplated.
Various proteases can be used to accomplish a specific cleavage.
The arrows indicate the specific cleavage points so far identified.
Cleaving the captured proteins with a sequence specific cleavage agent.
Often site specific cleavage sequences contained in template sequences are all identical.
The spacer would be framed by two identical protease specific cleavage sites.
A different sequence specific cleavage agent being used in the generation of each individual profile.
Digesting the proteins in the fraction with a sequence specific cleavage reagent.
The specific cleavage method is preferably a chemical cleavage method as will be further elucidated hereinbelow.
Full complementarity of bases closest to the ribonucleotides are more crucial to specific cleavage.
The present invention contemplates specific cleavage at any site within such a structure.
The captured proteins may then be cleaved with a sequence specific cleavage agent.
Specific cleavage agents often cleave specifically according to a particular nucleotide sequence at a particular site.
This method is based on phosphorothioate chemistry which allows the specific cleavage of phosphorothiodiester bonds.
See also
The specific cleavage of peptide bonds is a central mechanism for regulation of complex biological processes.
The coding molecules are released from the solid phase support by specific cleavage of a linker.
The specific cleavage with thrombin is made without digesting other important proteins in the blood.
A particularly critical factor is the efficiency of the means to cleave site specific cleavage sequences.
Specific cleavage was controlled by further SDS polyacrylamide gel analyses.
The linking region will then include a functional entity that allows for specific cleavage.
This results in specific cleavage of the secondary signal probes by the Cleavase enzyme.
These results show that the inclusion of KCl allows the generation of a specific cleavage product.
Specific cleavage can be verified, and the cleavage products isolated using the methods described above.
Particularly preferred are synthetic chromogenic substrates that form detectable chromophores upon specific cleavage by a protease.
I could reproduce in vitro the specific cleavage of PMEL by using a recombinant form of BACE2.
Such conditions are similar to those described above for cleaving the site specific cleavage sequences.
Treating the sample with a sequence specific cleavage reagent such as Trypsin or Lys-C ;.
Ribozymes are enzymatic RNA molecules capable of catalyzing the specific cleavage ofRNA.
The specific cleavage sites and enzymes may be used in accordance with the Manufacturer 's specifications.
Endonucleases can cleave double stranded DNA at sequence specific cleavage sites.
This example illustrates the specific cleavage sites for cathepsin S at the N-terminus of CLIP.
The inventors of the present invention have identified hitherto unknown specific cleavage sites of COMP.
Rz20 was designed to elicit mutation specific cleavage of transcripts containing a Pro23Leu rhodopsin mutation.
Once transcribed VS RNA undergoes a site specific cleavage.
Specific cleavage of FIXa substrate was monitored at 405nm in an ELISA reader.
Of course, any other appropriate method of base specific cleavage can be used if desired.
A 19-nucleotide catalytic region and a 24-nucleotide substrate were sufficient to support specific cleavage.
The product of specific cleavage by the tRzatp9 ribozyme ( 168 nucleotides ) is indicated with an arrow.
Contacting the C-terminally modified proteins with a sequence specific cleavage agent.
Similarly, target specific cleavage was achieved using a 13 nucleobase oligomer, including those with 1 or 3 mismatches.
The degradation sequence comprises a matrix metalloprotease ( MMP ) specific cleavage site.
Similarly, target specific cleavage was achieved using a 13 nucleobase ASOs, including those with 1 or 3 mismatches.
Ribozymes, enzymatic RNA molecules, may also be used to catalyze the specific cleavage of RNA.
In all cases sequence specific cleavage was obtained at the target cleavage sites ( Figs 1-7 ).
As expected, exposure of the hybrids to RNase H yielded specific cleavage products.
Figure 3 demonstrates mutation specific cleavage of the mutant RNA over time incublated at 37°C with 10mMMgCl2.
Fig . 1 describes this assembly and the specific cleavage site.
Already in 1988 a specific metalloprotease was postulated to be responsible for this specific cleavage.
Enteropeptidase exhibits trypsin-like activity, cleaving proteins following a lysine at a specific cleavage site Asp-Asp-Asp-Asp-Lys.
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