Examples of 'spliceosome' in a sentence
Meaning of "spliceosome"
spliceosome (noun): a complex of protein and RNA molecules that removes introns from pre-mRNA, allowing the exons to be connected to form a mature mRNA molecule
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- A dynamic complex of RNA and protein subunits that removes introns from precursor mRNA.
How to use "spliceosome" in a sentence
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spliceosome
The spliceosome is a critical component in the process of transcription.
Alternative splicing takes place in a large protein complex called the spliceosome.
The spliceosome gets there first.
At least five different kinds of snRNPs join the spliceosome to participate in splicing.
The spliceosome is a multisubunit complex that accomplishes this task.
The presence of a second type of intron and spliceosome has always been enigmatic.
Mutations in spliceosome genes have been found in various types of cancers.
This complex of RNA molecules and proteins is called the spliceosome.
The spliceosome is responsible for mrna maturation through intron removal.
The researchers first studied the RNA in the absence of the spliceosome.
A spliceosome is a large and complex molecular machine found primarily within the nucleus of eukaryotic cells.
The highly coordinated splicing event takes place in a large complex called the Spliceosome.
The minor spliceosome carries out its function through a different pathway from the major spliceosome.
Molecular architecture of Zinc chelating small molecules that inhibit spliceosome assembly at an early stage.
As that of spliceosome group I and group II perform splicing without requiring any protein.
See also
The complex at this stage is known as the spliceosome A complex.
The spliceosome catalyzes the removal of introns, and the ligation of the flanking exons.
Group I and II introns perform splicing similar to the spliceosome without requiring any protein.
These proteins ensure that the intron-exon boundaries are properly defined and recruit the spliceosome.
After rearrangement, complex C is formed, and the spliceosome is active for catalysis.
The spliceosome is another RNP often also known as the snRNP or tri-snRNP.
Figure 2 is a schematic representation of the spliceosome complex.
The spliceosome is a highly complex machinery within the eukaryotic cell, containing ~ 200 proteins and several SnRNPs.
Protein SmN, a nuclear protein component of the spliceosome.
Some eukaryotes have a second spliceosome, the so-called minor spliceosome.
Introns in nuclear protein-coding genes that are removed by spliceosome.
Fig . 3 ( b ) shows distributions of two or more spliceosome pathway mutations for these eight genes.
Westbrook and colleagues have discovered that MYC-driven cancers depend on the spliceosome to survive.
Examples of such spliceosome genes include, but are not limited to, those presented in Table 1.
After extensive remodelling, the catalytically active spliceosome is obtained.
Table 1, Spliceosome genes and potential diseases affected Spliceosome gene.
The pre-mRNA contains specific sequence elements that are recognized and utilized during spliceosome assembly.
U1 is a small nuclear RNA ( snRNA ) component of the spliceosome and is involved in pre-mRNA splicing.
Interactions of U6 snRNA within the catalytic centre of the spliceosome.
The spliceosome consists of five small nuclear RNAs ( snRNAs ; U1-6 ) in combination with a variety of proteins.
FIG . 2 is a schematic representation of the spliceosome complex.
Other studies have shown that Wbp11 is a component of the spliceosome.
The yeast ortholog Cwc24p is predicted to have a spliceosome function.
Uridine-rich small nuclear ribonucleoproteins ( U snRNPs ) are the building units of the spliceosome.
All of these uridine-rich snRNA, with the exception of U7, form the core of the spliceosome.
Splicing factor 3b is also a component of the minor U12-type spliceosome.
MRNA splicing occurs during transcription ( 36 ) mediated by splicing proteins which form the spliceosome ( 5 ).
