Examples of 'staurosporine' in a sentence
Meaning of "staurosporine"
Staurosporine is a noun that refers to a potent antibiotic and antifungal agent derived from a bacterium
Show more definitions
- An alkaloid derived from the bacterium Streptomyces staurosporeus that has antifungal and antihypertensive properties
How to use "staurosporine" in a sentence
Basic
Advanced
staurosporine
Staurosporine is added to each plate as an inhibition control.
The method uses a medicament containing a staurosporine derivative.
Staurosporine was the positive control drug.
The control compound was staurosporine.
Staurosporine has been offered as an insecticide.
The present invention further relates to a novel staurosporine derivative.
Staurosporine was used as reference compound.
Pharmaceutical compositions containing staurosporine derivatives and a polyalkylene glycol glyceride.
Staurosporine is an indolocarbazole.
The results clearly demonstrate that the staurosporine derivative inhibits retinal neovascularization.
Staurosporine was found to be an effective TPA inhibitor for both of these actions.
These results clearly demonstrate that the staurosporine derivative dramatically inhibits chorodial neovascularization.
A similar rate of DNA fragmentation was obtained with the drug staurosporine.
This indicates that the staurosporine derivative inhibits retinal vascular development.
For maximal apoptosis of these targets, staurosporine was used.
See also
This demonstrates that the staurosporine derivative is not toxic to endothelial cells of mature vessels.
Indole derivatives, such as staurosporine.
This invention relates to rebeccamycin and staurosporine derivatives obtained by fermentation of recombinant bacterial strains.
Staurosporine was found to bean effective TPA inhibitor for both of these actions.
A pharmaceutical composition comprising a solution or dispersion of a staurosporine active ingredient in a saturated polyalkylene glycol glyceride.
For example, staurosporine or a synthetic staurosporine derivative are used as reference compounds.
StaG and StaN are enzymes of the staurosporine formation route.
As a control, resting lymphocytes and PHA-stimulated lymphocyte were treated with staurosporine.
The control compound Staurosporine was included on each test plate.
The stable expression resulted in a resistance of the cells to an apoptosis inducing agent, staurosporine.
Multi-parameter imaging of staurosporine treated cells.
Staurosporine ( STS ) was used as a possitive control inducing cellular mortality.
Viable cells were counted 24 hours after exposure to staurosporine by trypan blue exclusion.
Staurosporine did not inhibit the gluconeogenic responses to NE in pyruvate-perfused kidneys.
This invention relates to pharmaceutical compositions, particularly pharmaceutical compositions comprising a staurosporine as active ingredient.
Alternatively, ADP or staurosporine may be used for this application.
Figure 9 ; Scatterplot of indicator distribution in HeLa cells exposed to dexamethasone and staurosporine.
NM staurosporine was found to completely prevent the decrease of Rt induced by pZ14 supernatant.
These observations were also limited to the staurosporine model or a TNF-a mechanism in HUVEC.
Staurosporine and its derivatives, The biological efficacy of staurosporines is described by D. Fabbro et al.
In contrast, the non-specific inhibitor staurosporine potently inhibited the kinase activity of Akt.
Staurosporine is shown with carbon, nitrogen, and oxygen.
Results from analysis with these two algorithms on staurosporine treated cells are shown in Figure 10.
The biosynthesis of staurosporine starts with the amino acid L-tryptophan in its zwitterionic form.
A method according to claim 12, wherein the reference compound is staurosporine.
Staurosporine is a known anti-tumor agent having the following formula,.
As a positive control, the differentiating effect of 25nM staurosporine is shown.
Use staurosporine as positive control in this assay . Table 1.
Nonspecific reaction is determined in presence of 100 nM Staurosporine.
Staurosporine ( STS ) was used as a positive control inducing cellular mortality.
The procedure was repeated on d10, except that Staurosporine was omitted.
The pro-apoptotic agent staurosporine ( Staur ) at 1 mM was included as a positive control.
Crystalline human Mnk-2 kinase according to claim 7, wherein the inhibitor is staurosporine.
A composition according to claim 1, in which the staurosporine active ingredient is N-benzoylstaurosporine.
Staurosporine or Valproate, known inhibitors of GSK-3B, were used as a positive control for screening.