Examples of 'substantial challenges' in a sentence

Meaning of "substantial challenges"

substantial challenges: This phrase refers to significant or important difficulties or obstacles that need to be overcome

How to use "substantial challenges" in a sentence

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substantial challenges
There are substantial challenges in providing access to all.
These statistics present substantial challenges.
These are substantial challenges in any negotiating framework.
These new realities bring with them substantial challenges and opportunities.
There are substantial challenges related to biodiversity in areas outside national jurisdiction.
A large number of developing countries were expanding pension systems in spite of substantial challenges.
We face substantial challenges in the region.
Impassable roads and damaged communications infrastructure posed substantial challenges to rescue efforts.
These pose even more substantial challenges to measurement experts.
Morocco has limited availability of water resources and faces substantial challenges in this regard.
European countries face substantial challenges in developing their health systems.
In the early days of your presidency you have indeed been faced with substantial challenges.
I know that there are substantial challenges to be met in each of these areas.
However, we need to continue to surmount substantial challenges.
States face substantial challenges in developing their capacity to improve maritime security.

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Healthcare systems in the EU are expected to face substantial challenges in the future.
There appeared to be no substantial challenges to the voter register at polling stations observed.
In particular, data synchronization and consistency become substantial challenges.
It is confronted with substantial challenges which ACR itself has acknowledged.
In a complex design framework, standard variance estimation methods entail substantial challenges.
The complex geology in Kemi chrome mine has caused substantial challenges during underground mining operations.
We also face substantial challenges in implementing the Passenger Name Record Directive.
At the same time, we are concerned that substantial challenges still remain.
Nonetheless, substantial challenges to obtaining sufficient support remain.
On the other hand, the new data come with substantial challenges.
Substantial challenges still remained, however.
The rising prevalence of dementia imposes substantial challenges for patients, families, and societies.
Substantial challenges remain to be addressed, in particular comprehensive security sector reform.
It saw progress on women 's rights but raised concerns over the remaining substantial challenges.
Understanding substantial challenges caused by substance use, misuse and dependence.
Although local voluntary action offers a wealth of advantages to communities, it also brings substantial challenges.
Indonesia has overcome substantial challenges to establish the governance institutions of a democratic market-based state.
Yet, instituting a policy framework for combating counterfeiting and piracy poses substantial challenges.
However, substantial challenges such as tax avoidance, tax evasion and illicit financial flows remain.
While substantial progress has been made in reducing costs of ethanol production, substantial challenges remain.
These initiatives had both substantial challenges and risks, which would need careful management.
It saw progress on women & apos ; s rights but raised concerns over the remaining substantial challenges.
However, substantial challenges remain on the path to a European wide deployment.
Despite the gains in employment, women workers still face substantial challenges in all the regions.
Substantial challenges remain in the Government 's effort to achieve reform and accountability.
In spite of this positive evolution, Nicaragua still faces substantial challenges.
Yet substantial challenges remain, leading to a critical re-appraisal of the MDG framework.
In both Ethiopia and Eritrea, the humanitarian situation continued to pose substantial challenges.
Substantial challenges remain in the Government & apos ; s effort to achieve reform and accountability.
You will be in my prayers, for I know you have some substantial challenges ahead.
However, substantial challenges remained in the Government effort to achieve reform, transparency and accountability.
In the United States and further afield, anxiety and depression are substantial challenges.
Substantial challenges lay ahead, but the Organization had improved its capacity to meet those challenges.
At present, large-scale culturing of human ES cell lines is problematic and provides substantial challenges.
Permit to respond to the 4 substantial challenges concerning food,.

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Examples of using Challenges
There are critical challenges that require attention
Challenges regarding access equitable access dimension
We believe that those challenges are not insurmountable
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Examples of using Substantial
Both had substantial annual treatment costs
In percentage terms these welfare gains are substantial
We look forward to a substantial outcome of that conference
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