Examples of 'suicide gene' in a sentence
Meaning of "suicide gene"
Suicide gene is a term used in genetics to describe a gene that can be introduced into cells to cause cell death under specific conditions, often used in cancer research
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- Any gene that causes a cell to kill itself through apoptosis.
How to use "suicide gene" in a sentence
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suicide gene
The bug had a suicide gene.
India farmers suicide gene manipulation debt monsanto industry.
The bug has a suicide gene.
Such a suicide gene would be a particular advantage for graft eradication if necessary.
A gene having such a function is called suicide gene.
The expression of the suicide gene only kills dividing cells.
Seeds that will destroy themselves through a suicide gene.
A suicide gene is a gene which will cause a cell to kill itself through apoptosis.
There are currently two methods of suicide gene therapy being used.
These studies show a regression of established tumors after in vivo transfer of a suicide gene.
Utilization ofa suicide gene.
The suicide gene used is the thymidine kinase gene of the herpes simplex virus.
The poxvirus of the invention further comprises a suicide gene.
The third method is a method of introducing a suicide gene into the artificial genetic circuit.
The healthspan of mice is enhanced by killing senescent cells using a transgenic suicide gene.
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In a preferred embodiment, a suicide gene is used as the foreign antigen.
The oncolytic virus according to any of the preceding claims further comprising a suicide gene.
Desirably, the suicide gene encodes a protein having at least a CDase activity.
Utilization of a suicide gene.
Thus the invention also provides a use wherein said gene delivery vehicle further comprises a suicide gene.
A suicide gene encodes a protein able to convert a relatively non-toxic prodrug to a toxic drug.
Use of mesenchymal stem cells genetically modified to express a suicide gene for treating a cancer.
Another example of a suicide gene and a non-toxic prodrug is thymidine kinase and ganciclovir.
Examples of therapeutic genes are tumor suppressor genes and the suicide gene thymidine kinase.
A exogenous suicide gene may be expressibly incorporated in addition to the above-described thymidine kinase gene.
The CAR expression vector of the present invention may contain a nucleic acid encoding a suicide gene.
The suicide gene strategies may not act quickly enough to eliminate off-tumor cytotoxicity as well.
In another embodiment, the accessory gene is an inducible suicide gene.
CodA can be used as a metabolic suicide gene in combination with the prodrug 5-fluorocytosine.
In a preferred embodiment of the invention, the exogenous sequence is a suicide gene.
In a further embodiment, the suicide gene is a caspase 9 suicide gene.
Further, the recombinant expression vectors can be made to include a suicide gene.
It has a suicide gene that stops it from replicating after 32 hours.
Once infected, the cancerous cells will express the suicide gene.
In specific embodiments, the inducible suicide gene is inducible caspase-9 suicide gene.
The expression vector of claim 7, wherein the heterologous gene is a suicide gene.
It has a suicide gene that stops it from replicating after 32 hours, as a security precaution.
The use of claim 9, wherein said fibroblasts are further modified to express a suicide gene.
The suicide gene used in the present invention is cytosine deaminase ( CD ).
Alternatively, tumor cells that can be cultured may be transduced with a suicide gene.
Pharmacologic activation of the iCasp-9 suicide gene efficiently eliminates gene-modified T cells in leukemia patients.
The use of claim 6, wherein said expression vector additionally contains a suicide gene.
A particularly preferred example of such a suicide gene is mammalian cytochrome P450.
The method of claim 1, wherein said expression vector further comprises an inducible suicide gene.
More preferably, said suicide gene is codA or codA,, upp.
Said transgene can also be a gene encoding a molecule of therapeutic interest and / or a suicide gene.
The TK-HSV-1 suicide gene may be mentioned more especially.
In addition, strategies using defective interfering DNAs and a suicide gene have been investigated.
Replacement of the RTA suicide gene carried by the pINT-MOS by the H1-1 gene.
According to a particularly preferred embodiment, the poxvirus of the invention further comprises a suicide gene.
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Suicide was outlawed by men avid to control souls
Prevention of child suicide and its monitoring
Examples of using Gene
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Gene will never be able to digest them
The baldness gene was cause for dread
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