Examples of 'sulfonyl chloride' in a sentence
Meaning of "sulfonyl chloride"
sulfonyl chloride: a chemical compound commonly used in organic synthesis and pharmaceutical manufacturing
How to use "sulfonyl chloride" in a sentence
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sulfonyl chloride
The sulfonyl chloride produces a sulfonamide linkage.
An excess of a suitable sulfonyl chloride is added.
The sulfonyl chloride was used without further purification.
The sulfonylating can be methane sulfonyl chloride or toluene sulfonyl chloride.
Sulfonyl chloride is also generally expensive.
Sulfonamides are prepared by the reaction of a sulfonyl chloride with ammonia or an amine.
The sulfonyl chloride immediately solidifies in the reaction flask.
The resulting substituted halobenzene sulfonyl chloride is then treated as described above.
The sulfonyl chloride for example may be mesyl chloride or tosyl chloride.
The present invention also relates to the preparation of trifluoromethane sulfonyl chloride.
The preferred sulfonyl chloride is methanesulfonyl chloride.
The filtrate is concentrated under vacuum to give the crude sulfonyl chloride.
The intermediate sulfonyl chloride obtained as an oil was not isolated.
Thioglycolic acid is developed as a new sulfur transfer agent for sulfonyl chloride synthesis.
This substituted sulfonyl chloride is reacted with a suitable amine.
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The free amine is then sulfonylated with the appropriately substituted sulfonyl chloride.
G of sulfonyl chloride is obtained which is immediately employed for the preparation of sulfonamide.
The reaction gave a mixture of sulfonyl chloride and another product as a white solid.
The sulfonyl chloride can then be converted its aminoaryl sulfonamide as described previously.
At least one equivalent of base is required for each equivalent of the sulfonyl chloride.
The desired sulfonyl chloride was washed with cold water and hexane.
Removal of the solvent at atmospheric pressure afforded the sulfonyl chloride as a crude dark oil.
Finally the sulfonyl chloride is coupled with an amine to give the corresponding sulfonamide.
The acid is then reacted with thionyl chloride to give the corresponding aryl sulfonyl chloride.
The thus formed sulfonyl chloride is then used crude in Method A.
NMR analysis revealed that the isolated crude was the double sulfonyl chloride addition product.
The starting sulfonyl chloride is prepared as follows,.
Sulfonating the amide of formula IV to provide a sulfonyl chloride V.
A process for producing a sulfonyl chloride compound comprising,.
The sulfonyl chloride can be reacted with an amine or alcohol as follows,.
In certain embodiments, a tosylate is a sulfonyl chloride such as p-toluenesulfonyl chloride.
A method according to claim 11 wherein the activation agent is a sulfonyl chloride.
Alternatively, a halobenzene sulfonyl chloride may be reacted with a pyrrole.
Crosslinking functionalities include the various silanes, and sulfonyl chloride.
Unless otherwise stated, each sulfonyl chloride was a commercially available material.
The sulfonyl chloride includes methanesulfonyl chloride, p-toluenesulfonyl chloride or the like.
The acylating agent is typically a chloroformate or a sulfonyl chloride as shown in chart 4.
The sulfonyl chloride was filtered, washing with water to afford a white solid.
Process according to claim 2 wherein the tosyl halide is p-toluene sulfonyl chloride.
The benzene sulfonyl chloride may be added all at once, or in separate portions.
A mesylate compound f is formed in step 4 by treatment of alcohol e with methane sulfonyl chloride.
The organic acid anhydride or sulfonyl chloride is added continuously to the receiver vessel ;.
The substituted aryl group is further preferably paratoluene sulfonyl chloride ( tosyl chloride ).
The sulfonylating can be sulfonyl chloride, methane sulfonyl chloride or toluene sulfonyl chloride.
The protected alcohol 52 can be activated such as by reaction with methane sulfonyl chloride.
The organic acid anhydride or sulfonyl chloride is selected, trifluoroacetic anhydride or methanesulfonyl chloride ;.
Heating with phosphorus pentachloride furnishes the corresponding sulfonyl chloride 12 as a distillable liquid.
Preferred compounds are the sulfonyl chloride or esters, and the sulfonyl chlorides are most preferred.
The mixture was stirred three hours, then concentrated in vacuo to give the sulfonyl chloride.
Preferred reactive compounds are the sulfonyl chloride or esters ; the sulfonyl chlorides are most preferred.
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The sulfonyl chloride produces a sulfonamide linkage
Pharmaceutically active sulfonyl amino acid derivatives
Sulfonyl chlorides are reactive sulfonic acid derivatives
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