Examples of 'sulindac' in a sentence
Meaning of "sulindac"
Sulindac is a nonsteroidal anti-inflammatory drug that is used primarily to treat conditions affecting the joints, such as arthritis
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- A non-steroidal anti-inflammatory drug used as an analgesic and antipyretic
How to use "sulindac" in a sentence
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sulindac
Especially preferred NSAIDs are indoniethacin and sulindac.
Taking sulindac with anticoagulants increases your risk of bleeding.
Especially preferred NSAIDs are indomethacin and sulindac.
A standard solution of sulindac sulfide was used to obtain the calibration curve.
Important considerations for taking sulindac.
The effects of sulindac sulfide and exisulind on various cell lines were determined.
Eflornithine in combination with sulindac.
These data show that both sulindac sulfide and exisulind inhibit phosphodiesterase activity.
How to store sulindac.
You should not take sulindac if you will be having coronary artery bypass graft surgery.
Check your blood pressure before you start and while you take sulindac.
Sulindac was examined for suppression of TNFa induced AKT activation.
The third treatment was a combination of DFMO and sulindac.
Another NSAID is sulindac that has a side effect profile similar to indomethacin.
Transfection of RXRa enhances the apoptotic effect of Sulindac.
See also
Sulindac sulfide was reported also to bind Ras directly and interfere with nucleotide exchange.
Another interesting link between G proteins and colon cancer involves the drug sulindac.
The apoptotic effect of Sulindac was also reduced in cells transfected with RXRa siRNA Fig.
For example, EGCg was demonstrated to enhance the apoptotic effect of sulindac and tamoxifen.
Potential Sulindac activation of the extrinsic apoptotic pathway resulted in Bax activation was also examined.
Activation of Bax by Sulindac and TNFa.
Acetylsalicylic acid, sulindac and flurbiprofen showed lower elevations in blood pressure.
Suitable acetic acid derivatives include indomethacin, zomepirac, sulindac and the like.
Based on this, sulindac may be considered a prodrug.
In another aspect, the agent is an analog of Sulindac.
Sulindac is metabolized in vivo to two metabolites, sulindac sulfide and sulindac sulfone.
Figure 14 illustrates the effects of sulindac sulfide and exisulind on tumor cell growth.
Sulindac is a sulfoxide compound that itself is believed to be inactive as an anti-arthritic agent.
Cells treated with TNFa and / or Sulindac were analyzed by immunoblotting.
Taking sulindac with these drugs may reduce their blood pressure-lowering effects.
In another aspect of this embodiment, the agent is an analog of Sulindac.
In some animal studies, sulindac caused unwanted effects on the development of bones and organs.
Figure 6 shows the activation of a TNFa-induced extrinsic apoptotic pathway by Sulindac.
FIG . 2 depicts the chemical structures of certain other sulindac derivatives reported to inhibit Ras.
HepG2 cells transfected with RXRa siRNA were treated with Sulindac.
For example, in some embodiments, sulindac may be used together with celecoxib.
After treatment, cells were purified and analyzed by HPLC for the presence of sulindac sulfide.
Sulindac was intuitively modeled to bind to COX-2 similar to indomethacin.
Specific antiinflammatory agents include diclofenac, ibuprofen, indomethacin, ketoprofen, naproxen, piroxicam and sulindac.
Figure 7 illustrates the effects of sulindac sulfide on cyclic nucleotide levels in HT-29 cells.
The NSAIDs that displayed anti-amyloidogenic activity were diclofenac, meloxicam, phenylbutazone, sulindac and tenoxicam.
These data show that sulindac sulfide, but not exisulind, is a COX-I inhibitor.
A549 cells stimulated with TNFa were treated with Sulindac or analogs.
Figure 2 shows Sulindac inducing RXRa-dependent apoptosis and Bax activation.
The inhibition of VEGF by 74 % demonstrates the additive effect when thalidomide and sulindac are combined.
Thus, Sulindac can interfere with RA-induced rapid RXRa-dependent AKT activation.
Figure 15 illustrates the growth inhibitory and apoptosis-inducing activity of sulindac sulfide and control ( DMSO ).
The docking of Sulindac to RXRa is shown in Fig . 7A.
The use according to Claim 5, wherein the NSAID is sulindac.
Mice given both sulindac and white tea had 80 % fewer tumors -- an average of six.
