Examples of 'sulphamate' in a sentence
Meaning of "sulphamate"
sulphamate (noun): a type of chemical compound that contains a sulfamate group. It is commonly used in various industrial processes
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sulphamate
The compounds comprise two sulphamate groups.
The sulphamate group is a substituent on the ring component.
The present invention relates to a sulphamate compound.
The sulphamate compounds comprise at least one ring component.
These steroid sulphatase inhibitors are sulphamate esters.
Thus the delivered sulphamate compounds have a high bioavailability.
Thus sulphamic acid may be added for example as sulphamate.
Examples of such inhibitors are sulphamate ester derivatives of steroids.
The compound of the present invention is referred to as a sulphamate compound.
Pharmaceutical compositions containing sulphamate derivatives as steroid sulphatase inhibitors.
The compound is a cyclic compound comprising ring system and a sulphamate group.
Preferably the sulphamate compound comprises at least one sulfanylhydrocarbyl group.
The compound of the present invention may have one or more sulphamate groups.
The more than one sulphamate groups need not be the same.
Even more preferably, these are sulphate and sulphamate.
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The present invention therefore provides sulphamate compounds which may have a reduced oestrogenic activity.
A preferred water-soluble salt of sulphamic acid is sodium sulphamate.
Preferably the compound is a sulphamate of Formula II.
Nickelling in a sulphamate bath under the following operational conditions,.
Thus, the present invention provides novel sulphamate compounds.
In one embodiment, preferably, the sulphamate compound is an oxyhydrocarbyl derivative of oestrone sulphamate.
In some embodiments, there may be more than one sulphamate group.
The term " sulphamate compound " means a compound comprising at least one sulphamate group.
R is the above-mentioned preferred formula for the sulphamate group.
The cyclic compound also includes a sulphamate group as further substituent ( s ) on the ring system.
Preferably, the compound of the present invention is a flavonoid or flavanoid sulphamate.
SYNTHESIS The sulphamate derivatives were prepared essentially as described previously29.
Electrolytic nickeling said pre-nickeled deposit in an acid bath of sulphamate type.
The sulphamate group is attached to the 3 position of the A ring.
After said prenickeling step, subjecting said deposit to electrolytic nickeling in an acid sulphamate bath.
Preferably, the sulphamate group has the Formula III.
Examples of sulphur-containing compounds are zinc sulphide, ammonium sulphate, ammonium sulphamate and melamine sulphate.
The bridging O-atom of the sulphamate moiety in EMATE is important for inhibitory activity.
Compounds of the present invention have the formula: wherein R denotes a sulphamate group as described above.
The bridging O - atom of the sulphamate moiety in EMATE is important for inhibitory activity.
In one preferred aspect R1 is preferably a sulphamate group.
COMPOUNDS SYNTHESISED The following sulphamate derivatives were synthesised from the following parent compounds,.
A sulphamate compound according to claim 3 wherein each substituent is independently selected from C3 alkyl or C3 alkenyl.
The present invention also covers substituted variants of the sulphamate of the benzoflavone of Figure 10.
SULPHAMATE GROUP In one embodiment, the ring X has a sulphamate group as a substituent.
Typically, the sulphamate group has the formula,.
The water-soluble salts of sulphamic acid can be alkali-metal or an alkaline-earth-metal salts of sulphamate.
The hydrochloride, hydrobromide, lactate, acetate, sulphate, sulphamate and the like together with a pharmaceutically acceptable carrier.
Cobalt sulphamate as a source of Co++ ions for simultaneous deposition together with the nickel ;.
Preferably, R is the above-mentioned preferred formula for the sulphamate group.
These 9 sulphamate bath compositions are detailed in Table 1.
Preferably, R is the above-mentioed preferred formula for the sulphamate group.
A sulphamate compound according to claim 16 wherein R1 is a methoxy group.
In one aspect R1 is a sulphamate group.
A sulphamate compound according to claim 14 wherein R1 is an alkoxy group.