Examples of 'survivin' in a sentence
Meaning of "survivin"
survivin (adjective): Continuing to exist or live, especially in difficult circumstances
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- A protein that inhibits caspase activity
How to use "survivin" in a sentence
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survivin
It is targeted at survivin which prevents cells dying.
Survivin is a member of the inhibitor of apoptosis family.
Cell lysates were analyzed for survivin protein content.
Survivin showed no predictive or prognostic value.
There are disclosed peptide fragments of full length survivin.
Survivin is normally expressed during embryogenesis.
New wirings in the survivin networks.
Survivin might do the same.
Regulation of and through survivin has been described by several mechanisms.
Survivin has also been identified as a target for cancer therapy.
Several therapeutic approaches using survivin as target have been initiated.
Survivin has recently been found to play a role in cell cycle regulation.
Vaccines of the invention comprise one or more survivin antigens.
Looks like they been survivin on the road all through this thing.
The modulation is ultimately a change in the amount of survivin produced.
See also
Survivin appears to be involved with inhibition of apoptosis as well as cell cycle control.
The natural variants result in particular from the polymorphism of survivin.
Method for improving the efficacy of a survivin vaccine in the treatment of cancer.
Survivin is essential to the correct execution of mitosis and completion of cell division.
Compositions and methods for treating tumors presenting survivin antigens.
Expression of survivin correlates with advanced grade and invasiveness in several cancers.
The vaccine compositions of the invention comprise at least one survivin antigen.
Isolated survivin reactive CTLs lyse tumour cell lines of different origin.
Compounds of the present invention have been shown to inhibit the expression of survivin.
Survivin acts in concert with the mitotic spindle apparatus to regulate cell division.
Cerasome decreased expression of survivin and may lead to a therapeutic approach for fatal leukemia.
Survivin seems to be capable of regulating both cellular proliferation and apoptotic cell death.
The disclosed method stimulates a cell mediated immune response to survivin expressing cancer cells.
Only the marker survivin has shown as a predicting factor for poor tumor response.
Such oligonucleotides have been shown to modulate the expression of Survivin.
Survivin antigens of the invention also encompass variants and functional equivalents of survivin peptides.
CTL response to survivin in melanoma patients.
Survivin is a member of the LAP family of antiapoptotic proteins.
The control band was derived from PCR of a survivin cDNA.
They showed that survivin inhibited processing of these two caspases into their active forms.
This cytoprotection to drug toxicity has been linked to a VEGF mediated upregulation of survivin expression.
Survivin is expressed in the majority of pancreatic adenocarcinomas Sarela et al.
PBMCs from a melanoma patient were incubated with peptide clusters from survivin library.
Thus inhibition of Survivin is shown to interfere with cytokinesis.
CTLs were isolated from a melanoma infiltrated lymph node using survivin coated magnetic beads.
Survivin is another member of the LAP family of antiapoptotic proteins.
Sometimes I think we are just survivin one fight to the next.
Survivin expression id presented normalised to GAPDH transcript stady state.
Sodium salts are particularly preferred forms of the Survivin ASO compounds described herein.
These data suggest that survivin represent a widely expressed tumor antigen recognized by autologous T cells.
In one embodiment, the protein is survivin.
These characteristics qualify survivin as a suitable TAA for both diagnostic and therapeutic purposes.
The DPX-Survivac vaccine is designed to target survivin.
Survivin mRNA was monitored with realtime PCR and normalised to GAPDH.
CTL response to survivin in CLL patients.
