Examples of 't-cell epitopes' in a sentence
Meaning of "t-cell epitopes"
t-cell epitopes : Specific regions of antigens that are recognized by T-cells of the immune system and play a crucial role in immune responses
How to use "t-cell epitopes" in a sentence
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t-cell epitopes
T-cell epitopes have generally been shown to be linear oligopeptides.
Some methods to predict T-cell epitopes were applied.
Preferably such fragments are coupled to a source of T-cell epitopes.
Identified T-cell epitopes were removed by amino acid substitution.
Some heterologous peptides are universal T-cell epitopes.
We have mapped helper T-cell epitopes on the RhD protein.
It also does not contain any immunodominant T-cell epitopes.
Other suitable immunodominant T-cell epitopes may be used at a later stage.
A vaccine may comprise such promiscuous T-cell epitopes.
Determining T-cell epitopes within a protein by a method comprising the steps of,.
Assessing and screening for T-cell epitopes from.
The known minimal T-cell epitopes on each peptide are indicated by underlining.
An effective vaccine must contain one or more T-cell epitopes.
Ad displaying T-cell epitopes from ovalbumin were constructed, produced and characterized in vitro.
Several techniques of identifying additional T-cell epitopes are recognized by the art.
See also
A series of antibodies were constructed with reduced numbers of potential T-cell epitopes.
A method for determining T-cell epitopes within a protein comprising the steps of,.
The potentially immunogenic sequences are modified to decrease or eliminate potential T-cell epitopes.
In particular, the peptides are preferably T-cell epitopes identified from Alternaria alternata proteins.
Therefore, these variant peptide sequences are much poorer potential T-cell epitopes.
The identification and modification of potential T-cell epitopes in these junctions is performed as follows.
Computational modelling of these three processes is required for accurate prediction of T-cell epitopes.
In the prior art, T-cell epitopes of allergens have been used for desensitisation purposes.
Over the years a number of other promiscuous T-cell epitopes have been identified.
According to a preferred embodiment of the present invention the truncated molecule lacks T-cell epitopes.
The identification and removal of potential T-cell epitopes from proteins has been previously disclosed.
The protein sequence is scanned by a computer-based algorithm for potential T-cell epitopes.
The identification of helper T-cell epitopes of TAA remains an important task in anti-tumour immunotherapy.
These changes can then be incorporated into the protein of interest to remove T-cell epitopes.
Promiscuous T-cell epitopes can be derived from naturally occurring immunogens of viral and bacterial origin.
Randomization of amino acids during library construction can potentially introduce novel T-cell epitopes.
These hypoallergenic molecules comprise one or more T-cell epitopes but lack IgE-binding capacity.
The amino acid substitutions are selected such that they avoid creating novel T-cell epitopes.
Such T-cell epitopes can be measured to establish MHC binding.
The resulting DeImmunized protein contains mutated amino acids such that genuine T-cell epitopes are eliminated.
Specific T-cell epitopes for immunoassay-based diagnosis of Mycobacterium tuberculosis infection.
Another important point is the issue of MHC restriction of T-cell epitopes.
Effect of promiscuous T-cell epitopes in a recombinant subunit vaccine against K. Thyrsites.
The AMPHI program has been used to predict T-cell epitopes Gao et al.
Identification of T-Cell Epitopes in Protease from Bacillus lentus and Human subtilisin.
This method confirms that XTEN polypeptides may have few or no predicted T-cell epitopes.
T-cell epitopes which may be necessary can likewise be derived on theoretical grounds, e . g.
AMPHI This program has been used to predict T-cell epitopes Gao et al.
Many T-cell epitopes are known.
Examples of universal T-cell epitopes include,.
In an organism, these sequence segments maybe processed into non-self T-cell epitopes.
Peptides comprising good, potential T-cell epitopes are listed in table 5.
This peptide, when altered by intestinal transglutaminase, has a high density of overlapping T-cell epitopes.
Accordingly, it would be desirable to eliminate potential T-cell epitopes from a peptide, polypeptide or a protein.
The polyepitope carrier protein should contain five or more CD4 + T-cell epitopes.
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At least four IgE epitopes have been identified
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T-cell vaccines are designed to induce cellular immunity
Protection of mice is not dependent on cytotoxic t-cell responses
T-cell priming was measured by the standard procedure
