Examples of 'taxane derivative' in a sentence
Meaning of "taxane derivative"
taxane derivative ~ Refers to a type of chemical compound that is derived from or related to taxanes, which are a class of compounds used in chemotherapy to treat cancer
How to use "taxane derivative" in a sentence
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taxane derivative
A taxane derivative having the formula wherein.
The intermediate is then converted to the taxane derivative.
A taxane derivative of the formula wherein.
The intermediate is then converted to a biologically active taxane derivative.
Preferably, the anticancer taxane derivative administered is a paclitaxel derivative.
The additional agent can also be a second taxane derivative.
Preferably, the anticancer taxane derivative administerd is a paclitaxel derivative.
One preferred component of the combination therapy described is a taxane derivative.
Thus, the process results in a taxane derivative of high purity.
The neoadjuvant chemotherapy may comprise the administration of a taxane derivative.
A pharmaceutical composition comprising taxane derivative isolated according to process of claim 1.
In a specific embodiment, chemotherapy includes treatment with a taxane derivative.
A pharmaceutical composition comprising taxane derivative prepared according to process of claim 1.
The method of claim 53 wherein said neoadjuvant chemotherapy comprises the administration of a taxane derivative.
A composition compnsing the taxane derivative of claim 1 and a pharmaceutically acceptable medium.
See also
Specifically, the present disclosure provides a method for preparing a water soluble taxane derivative.
The process according to claim 1, wherein the taxane derivative is anhydrous or a trihydrate.
The medium preferably comprises a lipid carrier, more preferably a liposome, associated with the taxane derivative.
The method as claimed in claim 5 wherein the taxane derivative is docetaxel or paclitaxel.
A taxane derivative of the formula or wherein Ph is phenyl, and.
A process for the preparation of a taxane derivative comprising,.
The taxane derivative of claim 1 wherein R and R1 are unsaturated aliphatic fatty acids.
Further provided herein is a method of administering a taxane derivative to an animal, preferably a human.
Taxane derivative having the formula, wherein,.
Wherein said camptothecin derivative has a camptothecin skeleton ; and wherein said taxane derivative has a baccatin skeleton.
A taxane derivative according to claim 1, wherein.
The kit of claim 7, wherein the taxane derivative is paclitaxel.
The taxane derivative of claim 3 wherein.
The use of claim 1, wherein the taxane derivative is paclitaxel.
A taxane derivative according to any one of claims 1 to 6, wherein.
The pharmaceutical composition of claim 10, wherein the taxane derivative is paclitaxel.
A taxane derivative according to claim 1, wherein R9a is hydroxy or acetoxy.
The use of claim 3 or claim 4, wherein the taxane derivative is paclitaxel.
The taxane derivative of claim 1 wherein X3 is optionally substituted ethyl, propyl, isopropyl, butyl or hexyl.
Further provided herein is a method of administering a taxane derivative to an animal, e.g., a human.
The taxane derivative of claim 1 wherein R ₁ is phenyl.
The probable mechanism for formation of 7-epimer of taxane derivative is summarized in Scheme 1.
A taxane derivative according to claim 9, wherein Z is methyl or methoxy.
Preparation of the water soluble taxane derivative of the present invention B-1.
The taxane derivative of claim 3 wherein R9 is hydrogen and R9a is hydroxy.
The water soluble taxane derivative according to any one of claims 1-4, characterized in that,.
A taxane derivative represented by the following formula 3, in which R1 represents trihaloacetyl.
The taxane derivative of claim 1 wherein X3 is cyclohexyl, cyclopentyl, cyclopropyl, or cyclobutyl.
A taxane derivative according to any one of claims 1 to 10, wherein R9a is acetoxy.
A taxane derivative according to any one of claims 1 to 3, wherein R31 is phenyl.
A taxane derivative according to claim 1 or claim 2, wherein R9a is hydroxy or acetoxy.
A taxane derivative according to any one of claims 1 to 10, wherein R9a is hydrogen.
The taxane derivative of claim 8, wherein Z1X1 is a group having the formula, or.
A taxane derivative according to claim 1, wherein R3 is phenyl.
A taxane derivative according to claim 7, wherein R7 is acetoxy.
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Examples of using Taxane
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A taxane derivative having the formula wherein
In one aspect the taxane is paclitaxel or docetaxel
Taxane drugs have good antitumor activity
Examples of using Derivative
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Derivative values are calculated using notional amounts
Marketable securities and derivative financial instruments
Derivative financial instruments designated as hedging instruments
