Examples of 'teriflunomide' in a sentence
Meaning of "teriflunomide"
teriflunomide (noun) - a pharmaceutical drug used to treat multiple sclerosis by reducing inflammation
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- The active metabolite of leflunomide.
How to use "teriflunomide" in a sentence
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teriflunomide
Teriflunomide was not mutagenic in vitro or clastogenic in vivo.
Pharmacokinetic interactions of teriflunomide on other substances.
Teriflunomide is eliminated slowly from the plasma.
There is no experience regarding teriflunomide overdose or intoxication in humans.
Teriflunomide also inhibits several tyrosine kinases.
After stopping treatment with teriflunomide.
Teriflunomide is the main metabolite of leflunomide.
Animal studies have shown excretion of teriflunomide in milk.
Teriflunomide for mult iple sclerosis.
During treatment with teriflunomide the following should be monitored.
Teriflunomide is considered a very safe drug.
The active substance is teriflunomide.
Teriflunomide is the main active in vivo metabolite of leflunomide.
Food does not have a clinically relevant effect on teriflunomide pharmacokinetics.
Teriflunomide was well tolerated with no major safety concerns.
See also
Aubagio is a medicine that contains the active substance teriflunomide.
Teriflunomide for multiple sclerosis.
Severe renal impairment had no impact on the pharmacokinetic of teriflunomide.
Fingolimod and teriflunomide are taken through a daily single dose.
No serious opportunistic infections occurred in patients treated with teriflunomide.
Teriflunomide forms from leflunomide vía rearrangement and ring opening.
Before starting treatment with teriflunomide the following should be assessed.
Teriflunomide should not be used in patients with conditions of severe hypoproteinaemia.
These occurred with a higher incidence than in the teriflunomide arms.
Teriflunomide is moderately metabolised and is the only component detected in plasma.
Mild and moderate hepatic impairment had no impact on the pharmacokinetic of teriflunomide.
Effect of teriflunomide on warfarin.
There are limited amount of data from the use of teriflunomide in pregnant women.
Teriflunomide may cause serious birth defects when administered during pregnancy.
The primary biotransformation pathway for teriflunomide is hydrolysis with oxidation being a minor pathway.
Teriflunomide may increase dasabuvir exposures and should be used with caution.
Blood pressure must be checked before the start of teriflunomide treatment and periodically thereafter.
The efficacy of teriflunomide is evident before steady state plasma concentrations are reached.
Blood pressure elevation should be appropriately managed before and during treatment with teriflunomide.
Teriflunomide remains in your blood for a long time after you stop taking it.
The immunomodulatory drugs teriflunomide and leflunomide have been shown to inhibit DHODH.
Teriflunomide is the active metabolite of Leflunomide.
A solid pharmaceutical formulation for Teriflunomide was developer for use in clinical studies.
Caution regarding potential concomitant immune effects is required when switching patients from teriflunomide to TYSABRI.
In case of ulcerative stomatitis, teriflunomide administration should be discontinued.
The adverse reactions were consistent with the safety profile for teriflunomide in MS patients.
It has been found that teriflunomide blocks the transcription factor NF-κB.
AUBAGIO contains the active substance teriflunomide.
Advantegeous embodiments of derivatives of teriflunomide are malononitrilamides and / or derivatives thereof.
Teriflunomide is the active metabolite of leflunomide, responsible for its therapeutic actions.
Advantageous embodiments of derivatives of teriflunomide are malononitrilamides and / or derivatives thereof.
Animals are more sensitive to the pharmacology, and therefore toxicity, of teriflunomide than humans.
Therefore, teriflunomide plasma concentrations should be measured before a woman begins to attempt to become pregnant.
Pharmaceutical composition according to claim 1, wherein teriflunomide is replaced by its prodrug leflunomide.
Teriflunomide is the only active metabolite of leflunomide, completely responsible for its therapeutic actions.
