Examples of 'tetracycline compounds' in a sentence
Meaning of "tetracycline compounds"
tetracycline compounds - These are a group of antibiotics that are used to treat various bacterial infections in humans and animals
How to use "tetracycline compounds" in a sentence
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tetracycline compounds
Novel controlled release formulations of tetracycline compounds.
The tetracycline compounds are administered without administering a bisphosphonate compound.
Protein glycosylation may not be affected by the administration of the tetracycline compounds.
Substituted tetracycline compounds for treatment of inflammatory skin disorders.
The NO associated state may be be treated by administering tetracycline compounds of the invention.
The tetracycline compounds of the invention may be administered systemically.
Alternatively, delivery of the tetracycline compounds includes topical application.
The tetracycline compounds for use in the invention have narrow spectrum antibacterial activity.
Preferably, the NO associated state can be treated by administering tetracycline compounds of the invention.
All novel substituted tetracycline compounds described herein are included in the invention as compounds.
Figure 6 is a histogram illustrating the inhibition of MAT LyLu tumor metastasis by tetracycline compounds.
This patent does not disclose novel tetracycline compounds which themselves have activity against resistant organisms.
The term also includes 4-dedimethylamino tetracycline compounds.
The substituted tetracycline compounds for use in the invention are compounds of formual I or VI.
Scheme 15 illustrates the general synthesis of 9-substituted aminoalkyl substituted tetracycline compounds.
See also
The tetracycline compounds of the invention may be essentially non-antibacterial.
In addition, similar methodology can be used to synthesize 9-substituted 4-dedimethylamino tetracycline compounds.
Certain of the substituted tetracycline compounds of the invention are shown below,.
In yet another embodiment, the invention pertains to a method for synthesizing 7 - and / or 9 - substituted tetracycline compounds.
In another embodiment, the tetracycline compounds of the invention are essentially non-antibacterial.
Substituted tetracycline compounds with good cytotoxicities are indicated with * in Table 1.
Certain substituted 4-dedimethylamino tetracycline compounds can be synthesized by the method shown in Scheme 1.
Examples of tetracycline compounds with this R9substituent include 9-naphthyl minocycline urea.
The terms " substituted tetracycline " and " substituted tetracycline compounds " include tetracycline compounds of formula I . sancycline.
Examples of tetracycline compounds with this R9 substituent include 9-propylglycineethylester minocycline HCl, and 9-methylglycineethylester minocycline.
The reactive 7 - and / or 9 - amino substituted tetracycline compounds are included as reactive intermediates.
Examples of tetracycline compounds include, tetracycline, chlortetracycline, oxytetracycline, demeclocycline, methacycline, sancycline ; doxycycline, and minocycline.
Other 7-aryl and alkynyl tetracycline compounds can be synthesized using similar protocols.
The 7-substituted tetracycline compounds of the invention can also be synthesized using Stille cross couplings.
Examples of the substituted tetracycline compounds of the invention include the compounds shown in Table 1.
Examples of tetracycline compounds with this R9 substituent include 9-butylacrylate minocycline.
In another embodiment, the tetracycline compounds of the invention have both antibacterial and non-antibacterial effects.
Examples of substituted tetracycline compounds of formula I include, for example, and pharmaceutically acceptable salts thereof.
The term " 7-substituted tetracycline compounds " includes tetracycline compounds with substitution at the 7 position.
Certain substituted tetracycline compounds of the invention had MIC 's less than about 10 µg / ml.
Examples of tetracycline compounds with this R9 substituent include N-t-butyl-minocycline HCl.
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Do not use tetracycline if you are pregnant or breastfeeding
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Tetracycline should not be administered due to allergies
Examples of using Compounds
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These compounds are not effective against spores
Delete volatile organic compounds content of products
These compounds are now under further investigation
