Examples of 'tgf-beta' in a sentence
Meaning of "tgf-beta"
tgf-beta (noun) - This term refers to Transforming Growth Factor Beta, a protein that plays a critical role in cell growth, cell differentiation, and other cellular functions. It is often studied in the fields of biology, medicine, and biotechnology
How to use "tgf-beta" in a sentence
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tgf-beta
Also present are growth factors like TGF-beta.
Cell surface expression of TGF-beta was not detectable.
Both cells increase their production of TGF-beta.
Team unveils new TGF-beta functions in liver cancer.
The protein is also a binding partner of TGF-beta.
Effects of pirfenidone on TGF-beta induced procollagen production were investigated.
Activins and inhibins are members of the TGF-beta superfamily.
Beside TGF-beta signaling endoglin may have other functions.
It is more preferred to inhibit the TGF-beta receptor kinase.
Compounds exhibiting TGF-beta inhibitory activity may be found by screening.
This protein also participates in the TGF-beta signaling pathway.
Regulation of TGF-beta signalling and responses by the transcriptional corepressor snon.
This gene encodes a member of the TGF-beta family of proteins.
In addition, TGF-beta antibodies are useful in diagnostic assays and immunoaffinity purification.
Tregs induce their effects by producing a protein messenger called TGF-beta.
See also
Many of the proposals for TGF-beta inhibitors have involved antibodies.
The TGF-beta binding-proteins referred to are preferably expressed in mammalian cells.
This makes it difficult to raise antibodies in mice against human TGF-beta.
Serotonin and TGF-beta pathways link diet to health and ageing.
The cell is usually one that overexpresses the TGF-beta receptor.
Biogen developed TGF-beta receptor inhibitors for the treatment of fibrosis.
Chondrogenic differentiation is induced in a chondrogenic induction medium which contains TGF-beta 3.
The TGF-beta survives passage all the way to the colon.
Skin biopsies have been used to test TGF-beta in patients with systemic sclerosis.
Accordingly, TGF-beta plays an important role in a very wide variety of biological processes.
Endoglin has been found to be an auxiliary receptor for the TGF-beta receptor complex.
Targeting TGF-beta has been proposed as a potential therapeutic measure for example in glaucoma.
It was demonstrated that AjA reduces the release of TGF-beta from SSc fibroblasts.
Similar to other TGF-beta family proteins, BMPs are highly conserved across animal species.
The present invention includes functional fragments of TGF-beta binding-protein genes.
As such, TGF-beta antagonists are known and are used for the treatment of various diseases.
All these cytokines, together with TGF-beta have been implicated in airway remodeling.
In other situations, the antibody is one that does not significantly block TGF-beta.
At early stages of the development of cancer, TGF-beta counters the formation of cancer.
Modified TGF-beta oligonucleotide for use in a method of preventing and / or treating an ophthalmic disease.
The present disclosure includes functional fragments of TGF-beta binding-protein genes.
In most cases, TGF-beta enhances extracellular matrix production and suppresses cell proliferation.
Activins are dimeric polypeptide growth factors that belong to the TGF-beta superfamily.
In addition, TGF-beta also fulfils important functions in the regulation of the immune system.
Compositions containing genetically modified lung cancer cells expressing a TGF-beta inhibitor.
Notch and TGF-beta signaling pathways have been implicated in biliary cell fate in vivo.
T cell subsets cultured with stimulators with TGF-beta are shown as closed circles.
In addition, there have been limited reports of isolation of mouse monoclonal antibodies against TGF-beta.
Targeting the TGF-beta receptor could have detrimental effects on other tissues of the body.
The present invention utilizes isolated and purified TGF-beta antagonist polypeptides.
A TGF-beta inhibitor is an agent that reduces the activity of the TGF-beta signalling pathway.
The present application also contemplates affinity-matured antibodies that bind TGF-beta.
Increased cell growth due to decreased TGF-beta growth inhibition may contribute to cancer development.
Thus, there is a need for agents that function as potent regulators of TGF-beta signaling.
The cells are then contacted with TGF-beta and the resulting metabolic effects examined.
