Examples of 'therapeutic index' in a sentence
Meaning of "therapeutic index"
Therapeutic index is a term used in pharmacology and medicine to describe the ratio between the maximum tolerated dose of a drug and the minimum effective dose. It is a measure of drug safety and effectiveness, with a higher therapeutic index indicating a wider margin of safety. The therapeutic index helps in determining the appropriate dosage and evaluating the overall benefit-risk profile of a medication
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- The ratio of the median toxic dose of a drug to its median effective dose, used to gauge the safety of a particular medication (a low therapeutic index indicates that the drug is easily overdosed).
How to use "therapeutic index" in a sentence
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therapeutic index
Compounds with a large therapeutic index are preferred.
The therapeutic index of phenylbutazone is low.
They therefore have an excellent therapeutic index.
The therapeutic index for this drug is low.
Nitroxyl donors with improved therapeutic index.
Their therapeutic index is compatible with their use as a medicine.
Said compounds have better therapeutic index.
Thus the therapeutic index for these drugs is narrow.
These compounds have a better therapeutic index.
A high therapeutic index is preferred.
This is consistent with an improved therapeutic index.
The higher the therapeutic index the better the antibiotic.
Fampridine has a narrow therapeutic index.
Their therapeutic index is compatible with their use as a medicinal product.
It is observed that the therapeutic index is much improved.
See also
Tobramycin is thus said to be a drug with a narrow therapeutic index.
The therapeutic index is defined as the ratio of efficacy to toxicity of a compound.
Warfarin has a narrow therapeutic index.
Therapeutic index of cortexolone derived compounds on a panel of cancer cell lines.
The introduction of the therapeutic index.
The therapeutic index is.
Conjugates that exhibit a large therapeutic index are preferred.
Use of ciprofloxacin is cautioned in patients on theophylline due to its narrow therapeutic index.
The prodrugs increase the therapeutic index of the drug.
An important parameter of any iodine pharmaceutical is its therapeutic index.
This approach boasts an extended therapeutic index and improved therapy.
Risperidone is a highly potent drug having a relatively narrow therapeutic index.
It also has a much higher therapeutic index than fentanyl and morphine.
Taxanes are toxic compounds having a low therapeutic index.
The drugs with a narrow therapeutic index were identified in tertiary source of reference in pharmacotherapy.
This provides compounds with a favourable therapeutic index.
Their therapeutic index is so low that even a double overdose has a toxic effect.
Acivicin has a good therapeutic index.
Utilizing desmethylpantoprazole results in enhanced dosage predictability and an improved therapeutic index.
Cyclosporine is an immunosuppressant drug with a narrow therapeutic index and large variability in pharmacokinetics.
Bioavailability data is especially important for products with a low therapeutic index.
Numerous attempts have been made to improve therapeutic index of camptothecin by modifying its structure.
It also showed that dexamethasone had a broad therapeutic index.
Consequently the therapeutic index for such moieties has proven to be relatively low.
These compounds also have an excellent therapeutic index.
The therapeutic index is the ratio between the lethal dosage and effective dosage.
These symptoms are attributable to the low therapeutic index of carisoprodol.
A therapeutic index was calculated by examining the least effective dose and the maximum tolerance dose.
Caution is advised when prescribing narrow therapeutic index drugs.
A low therapeutic index indicates that there is a high risk of toxicity when using the drug.
The compounds also possess a surprisingly high therapeutic index.
This compound also has an excellent therapeutic index and limited adverse reaction profile.
The disclosed compounds may exhibit a high therapeutic index.
There is a high therapeutic index since most antibodies spare the control cells from cell death.
This is particularly relevant for drugs with a narrow therapeutic index.
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Examples of using Therapeutic
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Therapeutic usefulness and appropriate use of benzodiazepines
This shows that therapeutic abortion is permitted
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