Examples of 'thiazolyl' in a sentence
Meaning of "thiazolyl"
thiazolyl (noun) - a chemical compound containing a thiazole ring structure, commonly found in pharmaceuticals or organic synthesis
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- a radical derived from thiazole
How to use "thiazolyl" in a sentence
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thiazolyl
Preferred heteroaromatic rings include pyridinyl and thiazolyl.
Most preferred are thiazolyl or pyridinyl.
Particularly preferred are halogenated pyridyl and halogenated thiazolyl.
These rings also include thiazolyl and triazolyl groups.
Y may be an optionally substituted thiazolyl.
The phenyl groups and optional thiazolyl groups can be substituted or unsubstituted.
A representative example is thiazolyl.
The thiazolyl group is preferably in the meta position with respect to the sulfonamide group.
Is preferably a substituted or unsubstituted thiazolyl or benzothiazolyl.
Preferably, thiazolyl group can be mentioned.
Another such class of antifungal compounds comprises the thiazolyl substituted benzimidazoles.
As thiazolyl and oxazolyl groups are neutral, they are hydrophobic.
Meloxicam is mainly metabolized by oxidation of the thiazolyl molecule in the methyl group.
An embodiment of the present invention includes compounds wherein A is thiazolyl.
The family of benzimidazoles with anthelmintic activity includes thiazolyl benzimidazoles and benzimidazole carbamates.
See also
Most preferred five-membered heteroaromatic ring is thiazolyl.
Represents a thiazolyl group or an isoxazolyl group ;.
Meloxicam is metabolized mainly through oxidation of the methyl group in the thiazolyl molecule.
In particular, it discloses thiazolyl derivatives comprising a bicyclic ring system.
The present compounds may also act as intermediates for the preparation of further thiazolyl derivatives.
The thiazolyl tetrazolium salts of the present invention are of the formula,.
Preferably Ar represents optionally substituted thiazolyl or pyrazolyl.
Among these, a thiadiazolyl group, a thiazolyl group or a pyrimidinyl group is more preferred.
In an even more preferred embodiment W represents a thiazolyl group.
In an embodiment, the aryl thiazolyl substituent is substituted with one or more substituents.
Especially preferred are pyridyl, thiazolyl and oxazolyl.
Furanyl, pyridyl or thiazolyl group, the furanyl group being optionally substituted with a halogen atom.
R is a substituted or unsubstituted thiazolyl unit having the formula,.
An example of a 5 membered heterocyclic group is thiazolyl.
Antibiotic derivatives, derived from cephalosporins with thiazolyl substituents, pharmaceutical preparations and salts thereof.
In some embodiments, the heteroaryl is thiazolyl.
When Ar2 is thiazolyl it is preferably unsubstituted.
The most preferred het are pyridyl, pyrimidinyl and thiazolyl.
This reaction can be employed to provide the thiazolyl and pyridyl reactants of formula ( III ).
Among the preferred heteroaromatic rings include pyridinyl, pyrimidinyl and thiazolyl.
More preferred W represents a thiazolyl group or a methyl-substituted thiazolyl group.
Nx is part of a fused ring, preferably fused with a thiazolyl ring.
A compound of Embodiment 5 wherein R2 is thiazolyl optionally substituted with halogen.
Advantageously, the heteroaryl group is chosen from furyl, pyridyl and thiazolyl groups.
A compound of Embodiment 6 wherein R2 is thiazolyl optionally substituted with Cl.
In a still further embodiment, Rd represents optionally substituted thiazolyl.
Preferable substituent R4 in the compounds of formula I-B are thiazolyl and pyridinyl substituted by halogen.
Examples of such heteroaryl groups as used for the substituent R1 are oxazolyl, and thiazolyl.
Furyl, pyridyl, oxazolyl, thiazolyl and thienyl are particularly preferred.
More preferred heteroaryl groups are thienyl, pyridyl, thiazolyl and benzothiazolyl.
The substituted thiazolyl wherein R20 is hydrogen is preferred.
Particularly preferred heterocyclic groups include pyrrolyl, imidazolyl, thiazolyl and oxazolyl.
The compound of claim 66, wherein said thiazolyl is substituted with a substituted or unsubstituted aryl.
Exemplary heteroaryl groups in this embodiment are pyrazolyl, pyridyl, thiazolyl and imidazolyl.
The present invention is concerned with 2,4,5-trisubstituted thiazolyl derivatives having proinflammatory cytokine production inhibiting properties.
