Examples of 'thrombomodulin' in a sentence
Meaning of "thrombomodulin"
Thrombomodulin is a protein that plays a role in the regulation of blood clotting and inflammation
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- An antithrombotic membrane protein on the surface of endothelial cells.
How to use "thrombomodulin" in a sentence
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thrombomodulin
Another is necessary for interacting with thrombomodulin.
Thrombomodulin is a membrane glycoprotein that can bind thrombin.
Figure shows the structural domains of human thrombomodulin.
Thrombomodulin is a plasma membrane proteoglycan.
Thrombin has the ability to bind reversibly to thrombomodulin.
Thrombomodulin is a membrane protein that has demonstrated anticoagulant properties.
Thrombin interacts with thrombomodulin.
Such actions possessed by thrombomodulin may be referred to as thrombomodulin activities.
Thrombin also binds to thrombomodulin.
A thrombomodulin gene used in a genetic recombination technique has been cloned.
Data are calculated as ratios to a normal pool with and without thrombomodulin.
Thrombomodulin is completely inactivated.
A cDNA molecule containing the gene encoding thrombomodulin is identified as described above.
Thrombomodulin is an endothelial cell membrane protein that acts as a receptor for thrombin.
The full length gene for thrombomodulin can be prepared by several methods.
See also
Another preferred example is affinity chromatography utilizing specific affinity with thrombomodulin.
The thrombomodulin of this embodiment may be prepared by a conventionally known method or a similar method.
Additional plasmids were constructed that contain other thrombomodulin analog gene sequences.
The method for producing thrombomodulin of this embodiment is not limited to the aforementioned method.
Endothelial products localized to the luminal endothelial surface include ectoADPase and thrombomodulin.
The activated endothelial cell is characterized by low thrombomodulin production and a permissive phenotype to hypercoagulability.
Examples of thrombomodulin used in this embodiment include the aforementioned preferred examples of soluble thrombomodulin.
A sequence of DNA encoding human thrombomodulin has been isolated.
Oxidation resistant thrombomodulin represents a new class of molecule suitable for creating a thromboresistant surface.
The Kd was determined for isolated preparations of recombinant thrombomodulin.
Soluble thrombomodulin analogs administered in conjunction with angioplasty will prevent this deleterious side effect.
The Ab also inhibits activation of protein by thrombin in the presence of thrombomodulin.
Thrombomodulin also accelerates the inactivation of thrombin by ATIII.
Protein C is cleaved to its activated form by the action of thrombin bound to thrombomodulin.
IHQ quantitation of thrombomodulin helped to diagnose mesothelioma when calretinin and CEA were both positive.
Said Ab inhibits thrombin interaction with fibrinogen and thrombomodulin but not thrombin amidolytic activity.
Information Disclosure Thrombomodulin is a membrane protein that has demonstrated anticoagulant properties.
After oxidation the cells were washed with PBS and assayed for cell bound thrombomodulin I.
Renal Ischemia Soluble thrombomodulin decreases leukocyte adhesion following renal ischemia.
Figure 2 shows the restriction map of thrombomodulin cDNA isolates.
Thrombomodulin forms a tight, stoichiometric complex with thrombin.
Both forms of sTM possess thrombomodulin activity, as described below.
Thrombomodulin analogs, including soluble molecules, having various modifications are known.
A multifunctional thrombomodulin analog comprised of,.
Figure 6 shows the chromosome localization of the human thrombomodulin gene.
Furthermore, thrombomodulin and an anticancer agent can also be simultaneously administered.
A sequence of nucleic acids encoding a multifunctional thrombomodulin analog comprising,.
Use of a thrombomodulin according to claim 1, wherein the analog is resistant to oxidation.
Alternatively, activity values are reported in comparison to native detergent solubilized rabbit thrombomodulin.
The full-length gene for thrombomodulin can be prepared by several methods.
Thrombomodulin functions as a receptor for thrombin, a central enzyme in the coagulation cascade.
It is preferred that the soluble thrombomodulin also has the anti-inflammatory action.
Use of an effective dose of a sterile aqueous solution of a multifunctional thrombomodulin analog comprising,.
Thrombomodulin is also expressed on human mesothelial cell, monocyte and a dendritic cell subset.
In another aspect of this invention, there are provided other improved compositions of thrombomodulin.
