Examples of 'thromboxane' in a sentence
Meaning of "thromboxane"
Thromboxane (noun): A type of eicosanoid compound that plays a role in blood clotting
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- Any of a number of eicosanoids, related to prostaglandin, that have a role in the clotting of blood
How to use "thromboxane" in a sentence
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thromboxane
The mechanism of inhibition of thromboxane formation is uncertain.
The results indicate an increased synthesis of thromboxane.
Thromboxane levels were measured in both milk and plasma.
Possibly endothelial prostacyclin without affecting platelet thromboxane.
Thromboxane is a member of the family of lipids known as eicosanoids.
Cyclooxygenase is required for prostaglandin and thromboxane synthesis.
A thromboxane inhibitor prevents blood clotting and preferably comprises aspirin.
Ifetroban is a potent and selective thromboxane receptor antagonist.
Treatment with thromboxane synthase inhibitors is therefore useful in this pathology.
These fatty acids will also reduce thromboxane.
Inhibition of the thromboxane synthase in washed platelets from human blood.
The compounds to which it relates are said to be inhibitors of thromboxane synthetase.
The thromboxane synthase inhibitors can be exemplified by imitrodast sodium and ozagrel hydrochloride.
Urinary levels of TxM serve as a measure of thromboxane turnover and thrombotic tendency.
Examples of the thromboxane synthetase inhibitors include ozagrel hydrochloride imitrodast sodium and the like.
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Such compounds may therefore be effective in the absence of an additional thromboxane synthetase inhibitor.
The thromboxane receptor has been expressed in Xenopus oocytes.
A benzimidazole derivative is described in said specification as a compound that has thromboxane receptor antagonistic activity.
Platelet thromboxane synthesis is also enhanced in patients with COPD.
BS is associated with overproduction of prostaglandins and thromboxane.
COX catalyzes the formation of prostaglandins and thromboxane by the oxidative metabolism of arachidonic acid.
Furthermore the compounds of formula I also inhibit blood platelet aggregation and inhibit thromboxane synthetase.
They did this by measuring levels of thromboxane ; thromboxane is an important platelet eicosanoid.
Thromboxane is a vasoconstrictor and a potent hypertensive agent, and it facilitates platelet aggregation.
Have demonstrated that estradiol potentiates the vasopressor response to a thromboxane mimetic in perfused rat lungs J.
Examples of the thromboxane antagonist include ozagrel, seratrodast and the like.
A composition according to claim 12 which additionally contains a thromboxane synthetase inhibitor.
Ticlopidine inhibits both thromboxane and ADP-induced platelet aggregation.
Thromboxane receptor antagonists ; together with a pharmaceutically acceptable carrier or diluent therefor.
A method according to claim 2, wherein the thromboxane concentration is determined using an immunoassay.
Aside from its anti-inflammatory effect, terutroban is a selective antagonist of the thromboxane receptor.
The inhibitors of the target effects of thromboxane are the thromboxane receptor antagonist, including terutroban.
This invention concerns 6-azaindole type compounds useful as thromboxane synthase inhibitors.
Examples of the thromboxane synthetase inhibitor include ozagrel hydrochloride, and imitrodast sodium, etc.
This invention concerns beta-carboline compounds useful as thromboxane synthase inhibitors.
Thus, thromboxane synthase plays a role in the pathogenesis of bone mineral density variation and osteoporosis.
In addition, certain of the compounds also selectively inhibit the thromboxane synthetase enzyme.
Thromboxane B2 data is expressed as a percentage of the levels measured in the vehicle control group.
In experimental animals, inhibiting cyclo-oxygenase or thromboxane synthase has protected against endotoxin shock.
The bioactive lipids derived from arachidonic acid include, for example, prostaglandins and thromboxane.
Researchers devised a way to block the platelet-activating thromboxane without affecting prostaglandin production.
A number of compounds also show an inhibitory action on the biosynthesis of thromboxane A2.
The objective compounds of this invention strongly inhibit thromboxane induced platelet agglutination, vasoconstriction, and bronchoconstriction.
Other compounds which may be administered along with the peptide derivative include thromboxane and EPIIb3a.
Seratrodast inhibits the activity of the thromboxane receptor, blocking the effects of TXA2.
It is irreversible inhibitor of cyclooxygenase in thrombocytes that prevents synthesis of thromboxane A2 in platelets.
Thromboxane A2 is also a known vasoconstrictor and is especially important during tissue injury and inflammation.
Method of action = = Terutroban is a selective antagonist of the thromboxane receptor.
Both thromboxane A2 and active analogues thereof are contemplated for use in the present invention.
The coloration developed is proportional to the amount of thromboxane B2 present in the sample.
