Examples of 'tolerogenic' in a sentence
Meaning of "tolerogenic"
tolerogenic (adjective) - pertaining to the induction or promotion of immune tolerance, a state in which the immune system does not react to specific antigens. Tolerogenic therapies aim to suppress autoimmune reactions and prevent rejection in transplant patients by promoting immune tolerance.
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- That produces immunological tolerance
How to use "tolerogenic" in a sentence
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tolerogenic
Disease therapy using a tolerogenic pharmaceutical preparation.
The tolerogenic vehicle may be recombinant or not.
Followed by establishment of a tolerogenic cytokine environment.
A clear tolerogenic response was promoted by natural mycolic acids in experimental asthma.
Mechanisms mediating the therapeutic effects of tolerogenic dendritic cells.
Validation of tolerogenic genes at the mRNA level by qPCR.
Higher expression of inhibitory molecules is associated with their tolerogenic abilities.
Compositions highly enriched for tolerogenic dendritic cells are achieved in this manner.
The fusión immunoglobulin has at least one heterologous tolerogenic epitope.
In an effort to search for tolerogenic peptides the culture conditions were successfully established.
This provides a possible explanation for the observed tolerogenic effect.
Suitable tolerogenic epitopes are those epitopes associated with allergic or autoimmune responses.
Mechanisms mediating the therapeutic effects of tolerogenic dendritic cells in allergic asthma.
The use of tolerogenic peptides to treat or prevent disease has attracted considerable attention.
In this way it is believed that the hyporesponsiveness or tolerogenic environment may be expanded.
See also
The tolerogenic cells are designed such that they generate an acceptance of the mature cells.
High amounts of red blood cells may thus favour the tolerogenic effect.
We also describe pharmaceutical compositions including a tolerogenic amount of a fusión immunoglobulin in a pharmaceutically acceptable excipient.
All these findings reveal that MSCs direct human DCs toward a tolerogenic phenotype.
Mode of administration can also influence the tolerogenic amount of the fusión immunoglobulin necessary.
The tolerogenic DCs may present the antigen to T cells.
The T cells are then cultured or incubated with tolerogenic dendritic cells.
How tolerogenic dendritic cells induce regulatory T cells.
Methods for the generation of a population of tolerogenic dendritic cells using factor H.
A tolerogenic epitope can interact with T cells or B cells or both.
Semi-mature dendritic cells are tolerogenic.
Alternatively, the tolerogenic cells may be directly induced in vivo.
Natural tol-DCs are mostly present in site of tolerogenic environment.
The liver 's tolerogenic APCs are implicated in the induction of this tolerance.
Figure 6 illustrates the characterization of new in vitro models of tolerogenic DCs.
It is believed that hla-f has tolerogenic and immune modulatory features.
The tolerogenic dendritic cells are characterized by showing one or more of the following features,.
Preferred non-pathogenic bacteria to be used as tolerogenic vehicles are commensal bacteria.
A tolerogenic response may, for example, allow the host to combat asthma or accept a graft.
Preferably, the screening assays for identifying tolerogenic epitopes are conducted in mice.
They too dictate the tolerogenic immutherapies for autoimmune disorders, including diabetes.
The same mechanisms may induce unrespon-siveness to tolerogenic forms of foreign antigens.
T13 contained in a non tolerogenic fraction was also synthetized as a negative control.
Still further embodiments relate to methods of generating an antigen-specific tolerogenic or regulatory immune response.
Embodiments of the invention include tolerogenic particles comprising a nanoparticle coupled to an antigen-MHC complex.
In certain embodiments, they are disclosed methods for producing antigen-specific tolerogenic dendritic cells.
Assessment of markers for effector / tolerogenic DCs in PBMCs from patients undergoing allergen-specific immunotherapy.
In certain embodiments, the invention provides methods for producing antigen-specific tolerogenic dendritic cells.
Feature of the tolerogenic cells are provided in Table 3.
In view of these results, BCG can thus be identified as a tolerogenic adjuvant.
Feature of the tolerogenic cells according to the present invention are provided in Table 3.
In a preferred embodiment, a method for the preparation of tolerogenic peptides comprises the following steps,.
A tolerogenic DC will exhibit higher expression of CD 14 than a mature immunostimulatory DC.
FIG . 6 illustrates the characterization of new in vitro models of tolerogenic DCs.
In such embodiments, the tolerogenic DCs may present the antigen to T cells.
